Original Article
Prognostic Significance of Glasgow Prognostic Score in Patients Undergoing Esophagectomy for Esophageal Squamous Cell Carcinoma Ji-Feng Feng1,2, Qiang Zhao1,2, Qi-Xun Chen1,2
ABSTRACT
1
Department of Thoracic Surgery, Zhejiang Cancer Hospital, No. 38 Guangji Road, Banshan Bridge, 2Key Laboratory Diagnosis and Treatment Technology on Thoracic Oncology, Zhejiang Province, Hangzhou, China
Address for correspondence: Dr. Ji-Feng Feng, Department of Thoracic Surgery, Zhejiang Cancer Hospital, Key Laboratory Diagnosis and Treatment Technology on Thoracic Oncology, No. 38 Guangji Road, Banshan Bridge, Hangzhou - 310 022, China. E-mail: [email protected]
Background/Aims: Recent studies have revealed that Glasgow prognostic score (GPS), an inflammation-based prognostic score, is inversely related to prognosis in a variety of cancers; high levels of GPS is associated with poor prognosis. However, few studies regarding GPS in esophageal cancer (EC) are available. The aim of this study was to determine whether the GPS is useful for predicting cancer-specific survival (CSS) of patients for esophageal squamous cell carcinoma (ESCC). Patients and Methods: The GPS was calculated on the basis of admission data as follows: Patients with elevated C-reactive protein (CRP) level (>10 mg/L) and hypoalbuminemia (
Prognostic Significance of Glasgow Prognostic Score in Patients Undergoing Esophagectomy for Esophageal Squamous Cell Carcinoma Ji-Feng Feng1,2, Qiang Zhao1,2, Qi-Xun Chen1,2
ABSTRACT
1
Department of Thoracic Surgery, Zhejiang Cancer Hospital, No. 38 Guangji Road, Banshan Bridge, 2Key Laboratory Diagnosis and Treatment Technology on Thoracic Oncology, Zhejiang Province, Hangzhou, China
Address for correspondence: Dr. Ji-Feng Feng, Department of Thoracic Surgery, Zhejiang Cancer Hospital, Key Laboratory Diagnosis and Treatment Technology on Thoracic Oncology, No. 38 Guangji Road, Banshan Bridge, Hangzhou - 310 022, China. E-mail: [email protected]
Background/Aims: Recent studies have revealed that Glasgow prognostic score (GPS), an inflammation-based prognostic score, is inversely related to prognosis in a variety of cancers; high levels of GPS is associated with poor prognosis. However, few studies regarding GPS in esophageal cancer (EC) are available. The aim of this study was to determine whether the GPS is useful for predicting cancer-specific survival (CSS) of patients for esophageal squamous cell carcinoma (ESCC). Patients and Methods: The GPS was calculated on the basis of admission data as follows: Patients with elevated C-reactive protein (CRP) level (>10 mg/L) and hypoalbuminemia (
