Selected Papers: Adult Epilepsy

444

Procedural Memory in Temporal Lobe Epilepsy

Table 2: Learning Ability Value and Age-Corrected Value Learning ability value

Mitsuharu Hidari, M.D., Mitsuhiro Fukai, M.D.,* Takehiko Okamura, M.D.,* Shinichi Kobayashi, M.D.,* Kyoko Hiroishi, M.D.,* Katsuhiro Toyoda, M.D.' and Toshiaki Sakai, M.D.*

Age-corrected value =Standard score of the normal controls-raw score

Departments of Laboratory Medicine and * Neuropsychiatry, Osaka Medical College Osaka

Table 3 :

- Trial 1 (sec.)-Trial 3 (sec.) Trial 1 (sec.)

Results of Memory Function Tests TLE

Introduction Squire classified memory into procedural and declarative memories.' The declarative memory is disturbed in patients with temporal lobe epilepsy' * 6; however, there is no report concerning the procedural memory. The aim of this study is to clarify whether or not the procedural memory is disturbed in patients with temporal lobe epilepsy (TLE). We compared the functions of procedural and declarative memories in TLE patients and in patients with idiopathic generalized epilepsy (IGE) , using four different meory function tests. Subjects and Methods Seventeen patients with TLE and 8 patients with IGE were studied at the ambulatory epilepsy clinic at Osaka Medical College Hospital (Table 1). The Tower of Hanoi and Mirror reading tests were carried out in 3 trials to evaluate the procedural memory. The 2nd trial was carried out 30 min. and the 3rd trial 2

Table 1: Subjects

Age (meanfSD) Sex (M/F) MMSE (meankSD) CT abnormality Therapy

TLE (n=17)

IGE ( n = 8 )

39.9f11.3 7/10 28.4+ 1.7 4 Mono: 8, poly: 9

26.6f4.8 5/3 29.8k0.5 0 Mono: 7, poly: 1

MVME -2.85f3.28 BVRT -2.OOf1.66 Tower of Hanoi 0.38f0.68 0.60f0.16 Mirror reading

IGE -2.2023.34 -0.48f1.05 0.56f0.33 0.47f0.21

NS P