J Gastrointest Canc (2014) 45 (Suppl 1):S265–S269 DOI 10.1007/s12029-014-9657-0

CASE REPORT

Primary Pancreatic Burkitt Lymphoma Presenting as Acute Pancreatitis Francesco Carbonetti & Elsa Iannicelli & Margherita Federici & Andrea Bucciarelli & Emanuela Pilozzi & Esmeralda Conte & Vincenzo David

Published online: 16 October 2014 # Springer Science+Business Media New York 2014

Introduction Primary pancreatic lymphoma (PPL) is an uncommon primary extra-nodal malignant non-Hodgkin’s lymphoma (NHL) of the pancreatic gland. More than 50 % of NHL arises in extranodal sites, frequently with the involvement of the gastrointestinal tract, in particular, the stomach and small bowel [1, 2]. Only 0.2–2 % of patients with NHL have pancreatic involvement at presentation, diffuse large B-cell lymphoma being the predominant type [3, 4]. PPL is an uncommon disease, less frequent than secondary involvement of the pancreas by NHL. Pancreatic lymphoma presenting as acute pancreatitis is rare [1, 2]. We report a case F. Carbonetti (*) : E. Iannicelli : M. Federici : A. Bucciarelli : V. David Department of Radiology, Sant’Andrea Hospital, University of Rome “La Sapienza”, Via di Grottarossa 1035, 00189 Rome, Italy e-mail: [email protected] E. Iannicelli e-mail: [email protected] M. Federici e-mail: [email protected] A. Bucciarelli e-mail: [email protected] V. David e-mail: [email protected] E. Pilozzi Department of Anatomic Pathology, Sant’Andrea Hospital, University of Rome “La Sapienza”, Via di Grottarossa 1035, 00189 Rome, Italy e-mail: [email protected] E. Conte Department of Haematology, Sant’Andrea Hospital, University of Rome “La Sapienza”, Via di Grottarossa 1035, 00189 Rome, Italy e-mail: [email protected]

of a primary pancreatic lymphoma, Burkitt type, presenting as acute pancreatitis in an adult female.

Case Presentation A 64-year-old woman was admitted to our emergency department due to a 1-week history of abdominal pain radiating to the dorsal region, jaundice, vomiting and 5 kg of weight loss. Her past medical history reports a breast cancer treated with mastectomy 16 years before; no other remarkable pathologies were referred. Physical examination showed epigastric pain; no palpable masses were present. Laboratory tests revealed increased levels of pancreatic and hepatic enzymes: amylase 540 U/l (normal range 0–130 U/l), lipase 6872 U/l (normal range 13– 104 U/l), serum glutamic-oxaloacetic transaminase (S-GOT) 1401 U/l (normal value in woman

Primary pancreatic Burkitt lymphoma presenting as acute pancreatitis.

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