British Journal of Urology (1975),47. 518 0
Short Case Report
Primary Amyloidosis of the Ureter: Case Report Primary amyloidosis is rare in the urinary tract, usually involving the bladder. 9 previous cases of solitary ureteral involvement have been reported (Johnson and Ankenman, 1964; Magri and Atkinson, 1970; Takaka et al., 1971). Mrs V. A., a 65-year-old woman, noted haematuria 3 months prior to consultation, in December 1972. Past health, physical examination, urinalysis and urine cultures were negative. IV urograms showed narrowing of the lower left ureter and hydronephrosis. Cystoscopy was negative. Retrograde pyelograms (Fig. 1) confirmed the narrowing of the ureter. Chest X-ray and urine cultures for tubercle bacilli were negative. Haematuria recurred and nephro-ureterectomy was performed in October 1973 with the presumptive diagnosis of ureteral tumour. Examination of the specimen showed a granular haemorrhagic lesion of the lower third of ureter 6 cm
Fig. 1
in length with ulceration. Microscopy with CongoRed stain (Fig. 2) showed replacement of muscle by amorphous eosinophilic material with a chronic inflammatory reaction and multinucleated giant cells. Blood vessels and adjacent fat were involved. Postoperatively, systemic Congo-Red tests and bone marrow aspirate were negative for amvloid. PHILIPG. KLOTZ Mount Sinai Hospital, Toronto, Ontario
References JOHNSON,H. W. and ANKENMAN, G. J. (1964). Bilateral ureteral primary amyloidosis. Journal of Urology, 92, 275. MAGRI,J. and ATKINSON,E. A. (1970). Primary amyloidosis of ureter. British Journal of Urology, 42, 37.
TAKAKA,M., NAGATA,H. and SONADA,T. (1971). Localized amyloid tumour of the ureter: report of a case. Journal of Urology, 105, 502.
Fig. 2. Microsco ic section through involved ureter showing amyloi8deposits. 518
Short Case Report
Primary Amyloidosis of the Ureter: Case Report Primary amyloidosis is rare in the urinary tract, usually involving the bladder. 9 previous cases of solitary ureteral involvement have been reported (Johnson and Ankenman, 1964; Magri and Atkinson, 1970; Takaka et al., 1971). Mrs V. A., a 65-year-old woman, noted haematuria 3 months prior to consultation, in December 1972. Past health, physical examination, urinalysis and urine cultures were negative. IV urograms showed narrowing of the lower left ureter and hydronephrosis. Cystoscopy was negative. Retrograde pyelograms (Fig. 1) confirmed the narrowing of the ureter. Chest X-ray and urine cultures for tubercle bacilli were negative. Haematuria recurred and nephro-ureterectomy was performed in October 1973 with the presumptive diagnosis of ureteral tumour. Examination of the specimen showed a granular haemorrhagic lesion of the lower third of ureter 6 cm
Fig. 1
in length with ulceration. Microscopy with CongoRed stain (Fig. 2) showed replacement of muscle by amorphous eosinophilic material with a chronic inflammatory reaction and multinucleated giant cells. Blood vessels and adjacent fat were involved. Postoperatively, systemic Congo-Red tests and bone marrow aspirate were negative for amvloid. PHILIPG. KLOTZ Mount Sinai Hospital, Toronto, Ontario
References JOHNSON,H. W. and ANKENMAN, G. J. (1964). Bilateral ureteral primary amyloidosis. Journal of Urology, 92, 275. MAGRI,J. and ATKINSON,E. A. (1970). Primary amyloidosis of ureter. British Journal of Urology, 42, 37.
TAKAKA,M., NAGATA,H. and SONADA,T. (1971). Localized amyloid tumour of the ureter: report of a case. Journal of Urology, 105, 502.
Fig. 2. Microsco ic section through involved ureter showing amyloi8deposits. 518
