Immunol. Cell Biol (1990) 68, 63-69
Prevention of adjuvant-induced cachexia in rats by cyclosporin A A. M. Rofe,' M. W. Whitehouse,^ C. S. Bourgeois," D. R. Haynes^ and B. Vernon-Roberts^' ^ Divisions of ^Clinical Chemistry and ^Tissue Pathology, Institute of Medical and Veterinary Science. Adelaide, and ^Department of Pathology, University of Adelaide, Adelaide. SA 5000, Australia (Submitted 4 August 1989. Accepted for publication 27 October 1989.) Summary The changes in food intake and biochemistry following Freund's adjuvant (AJ)-induced inflammation in rats were investigated. Injection of AJ into rats resulted in a transient anorexia but a sustained decrease in body weight. Within 14 days, body weight decreased by 12% {P
Prevention of adjuvant-induced cachexia in rats by cyclosporin A A. M. Rofe,' M. W. Whitehouse,^ C. S. Bourgeois," D. R. Haynes^ and B. Vernon-Roberts^' ^ Divisions of ^Clinical Chemistry and ^Tissue Pathology, Institute of Medical and Veterinary Science. Adelaide, and ^Department of Pathology, University of Adelaide, Adelaide. SA 5000, Australia (Submitted 4 August 1989. Accepted for publication 27 October 1989.) Summary The changes in food intake and biochemistry following Freund's adjuvant (AJ)-induced inflammation in rats were investigated. Injection of AJ into rats resulted in a transient anorexia but a sustained decrease in body weight. Within 14 days, body weight decreased by 12% {P
