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STI Online First, published on May 29, 2014 as 10.1136/sextrans-2014-051548 Epidemiology

ORIGINAL ARTICLE

Prevalence of HIV, HSV-2 and pregnancy among high school students in rural KwaZulu-Natal, South Africa: a bio-behavioural cross-sectional survey Quarraisha Abdool Karim,1,2 Ayesha B M Kharsany,1 Kerry Leask,1 Fanelisibonge Ntombela,1 Hilton Humphries,1 Janet A Frohlich,1 Natasha Samsunder,1 Anneke Grobler,1 Rachael Dellar,1 Salim S Abdool Karim1,2 ▸ Additional material is published online only. To view please visit the journal online (http://dx.doi.org/10.1136/ sextrans-2014-051548). 1

Centre for the AIDS Programme of Research in South Africa (CAPRISA), Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa 2 Department of Epidemiology, Mailman School of Public Health, Columbia University, Correspondence to Dr Quarraisha Abdool Karim, CAPRISA: 2nd Floor, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal/Private Bag 7, Congella 4013, Durban, South Africa; abdoolq2@ukzn. ac.za Received 29 January 2014 Revised 30 April 2014 Accepted 12 May 2014

ABSTRACT Objective Adolescents in southern African high schools are a key population for HIV prevention interventions. We report on the prevalence of HIV, HSV-2 and pregnancy as indicators of high-risk sexual behaviour among high school students in rural KwaZulu-Natal. Design Bio-behavioural cross-sectional survey. Methods Students completed a self-administered structured, standardised demographic and sexual behavioural questionnaire. Dried blood spot specimens were collected for HIV and HSV-2 testing. Urine specimens were used for pregnancy testing in female students. Results A total of 2675 (1423 females, 1252 males) consenting students were enrolled from 14 high schools between September and November 2010. The median age of students was 16 years (IQR 15–18). HIV prevalence was 1.4% (95% CI 0.9 to 1.9) in males and 6.4% (95% CI 4.6 to 8.3) in females ( p

Prevalence of HIV, HSV-2 and pregnancy among high school students in rural KwaZulu-Natal, South Africa: a bio-behavioural cross-sectional survey.

Adolescents in southern African high schools are a key population for HIV prevention interventions. We report on the prevalence of HIV, HSV-2 and preg...
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