Prevalence of diabetic retinopathy in Iran

·Meta-Analysis·

Prevalence of diabetic retinopathy in Iran: a systematic review and Meta-analysis Saman Maroufizadeh1, Amir Almasi-Hashiani1, Mostafa Hosseini2, Mahdi Sepidarkish1, Reza Omani Samani1 1

Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran 16635-148, Iran 2 Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran 14155-6446, Iran Correspondence to: Reza Omani Samani. Department of Epidemiology and Reproductive Health, Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran 16635-148, Iran. samani@ royaninstitute.org Received: 2017-02-06 Accepted: 2017-03-01

Abstract

● AIM: To estimate the overall prevalence of diabetic retinopathy (DR) in Iran by a systematic review and Metaanalysis. ● METHODS: We conducted a search of all published literature on diabetic patients for the prevalence of DR using Web of Sciences, PubMed, Scopus, Google Scholar, and national electronic databases SID, Magiran, and Iranmedex from their inception until September 2016 with standard keywords. Pooled estimates of the DR prevalence and the corresponding 95% confidence intervals (CI) were calculated using random effects models. ● RESULTS: Thirty-one studies involving 23 729 patients with type I and II diabetes were included. The publication bias assumption for prevalence of DR was rejected by Begg and Egger tests (P=0.825, P=0.057, respectively). The results of Cochran test and I2 statistics showed considerable heterogeneity for prevalence of DR (Q=1278.21, d.f.=30, P