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Clinical science
Prevalence and characteristics of plateau iris configuration among American Caucasian, American Chinese and mainland Chinese subjects Yingjie Li,1,2 Ye Elaine Wang,1,3 Guofu Huang,2 Dandan Wang,1,4 Mingguang He,4 Mary Qiu,1 Shan Lin1 1
University of California, San Francisco, California, USA 2 The Third Affiliated Hospital of Nanchang University, Nanchang, China 3 Duke University, School of Medicine, Durham, North Carolina, USA 4 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yatsen University, Guangzhou, China Correspondence to Dr Shan C Lin, Department of Ophthalmology, University of California, 10 Koret way, Room K301, San Francisco, CA 94143-0730, USA; [email protected] YL and YEW contributed equally. Received 29 May 2013 Revised 29 October 2013 Accepted 11 December 2013 Published Online First 15 January 2014
ABSTRACT Background To investigate the prevalence, risk factors and characteristics of plateau iris configuration (PIC) among American Caucasian, American Chinese and mainland Chinese. Methods This multicentre, cross-sectional study of non-glaucomatous subjects (40–80 years) included 111 American Caucasian, 116 American Chinese and 110 mainland Chinese. Prevalence of PIC based on ultrasound biomicroscopy imaging was compared among the different ethnic groups. Risk factors and anterior segment optical coherence tomography-measured iris and angle parameters in eyes with PIC were compared. Results The prevalence of PIC was 25.2% in American Caucasian, 24.1% in American Chinese and 20.9% in mainland Chinese ( p=0.73). The presence of PIC was associated with more positive spherical equivalence (OR=1.31, p=0.002) and shorter axial length (OR=0.75, p=0.04). There were significant differences in angle recess area (ARA) ( p=0.04), IT750 ( p=0.007) and IT2000 ( p
Clinical science
Prevalence and characteristics of plateau iris configuration among American Caucasian, American Chinese and mainland Chinese subjects Yingjie Li,1,2 Ye Elaine Wang,1,3 Guofu Huang,2 Dandan Wang,1,4 Mingguang He,4 Mary Qiu,1 Shan Lin1 1
University of California, San Francisco, California, USA 2 The Third Affiliated Hospital of Nanchang University, Nanchang, China 3 Duke University, School of Medicine, Durham, North Carolina, USA 4 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yatsen University, Guangzhou, China Correspondence to Dr Shan C Lin, Department of Ophthalmology, University of California, 10 Koret way, Room K301, San Francisco, CA 94143-0730, USA; [email protected] YL and YEW contributed equally. Received 29 May 2013 Revised 29 October 2013 Accepted 11 December 2013 Published Online First 15 January 2014
ABSTRACT Background To investigate the prevalence, risk factors and characteristics of plateau iris configuration (PIC) among American Caucasian, American Chinese and mainland Chinese. Methods This multicentre, cross-sectional study of non-glaucomatous subjects (40–80 years) included 111 American Caucasian, 116 American Chinese and 110 mainland Chinese. Prevalence of PIC based on ultrasound biomicroscopy imaging was compared among the different ethnic groups. Risk factors and anterior segment optical coherence tomography-measured iris and angle parameters in eyes with PIC were compared. Results The prevalence of PIC was 25.2% in American Caucasian, 24.1% in American Chinese and 20.9% in mainland Chinese ( p=0.73). The presence of PIC was associated with more positive spherical equivalence (OR=1.31, p=0.002) and shorter axial length (OR=0.75, p=0.04). There were significant differences in angle recess area (ARA) ( p=0.04), IT750 ( p=0.007) and IT2000 ( p
