BMJ 2014;349:g7430 doi: 10.1136/bmj.g7430 (Published 2 December 2014)
Page 1 of 1
Research News
RESEARCH NEWS Prehospital use of adrenaline reduces survival in cardiac arrest, study finds Susan Mayor London
The prehospital use of adrenaline (epinephrine) in patients in cardiac arrest is associated with an increased risk of death or debilitating brain damage, a large cohort study in France has found.
Guidelines recommend giving adrenaline every 3-5 minutes during resuscitation of patients in cardiac arrest, as it increases the likelihood of restoring spontaneous circulation. But the effects on long term survival have been uncertain.
Researchers analysed records of all patients with cardiac arrest occurring out of hospital who were admitted to a cardiac centre at a large Paris hospital from January 2000 to August 2012.1 Nearly three quarters (73%) of the 1556 patients were treated with at least one dose of adrenaline. Only 17% (194/1134) of these patients had a good outcome, defined as hospital discharge with normal or only moderately impaired brain function, compared with 63% (255/422) of those not treated with adrenaline (P
Page 1 of 1
Research News
RESEARCH NEWS Prehospital use of adrenaline reduces survival in cardiac arrest, study finds Susan Mayor London
The prehospital use of adrenaline (epinephrine) in patients in cardiac arrest is associated with an increased risk of death or debilitating brain damage, a large cohort study in France has found.
Guidelines recommend giving adrenaline every 3-5 minutes during resuscitation of patients in cardiac arrest, as it increases the likelihood of restoring spontaneous circulation. But the effects on long term survival have been uncertain.
Researchers analysed records of all patients with cardiac arrest occurring out of hospital who were admitted to a cardiac centre at a large Paris hospital from January 2000 to August 2012.1 Nearly three quarters (73%) of the 1556 patients were treated with at least one dose of adrenaline. Only 17% (194/1134) of these patients had a good outcome, defined as hospital discharge with normal or only moderately impaired brain function, compared with 63% (255/422) of those not treated with adrenaline (P
