Journal of Toxicology and Environmental Health
ISSN: 0098-4108 (Print) (Online) Journal homepage: http://www.tandfonline.com/loi/uteh19
Postlabeling analysis of polycyclic aromatic hydrocarbon‐DNA adducts in white blood cells of foundry workers M. Vijayaraj Reddy , Kari Hemminki & Kurt Randerath To cite this article: M. Vijayaraj Reddy , Kari Hemminki & Kurt Randerath (1991) Postlabeling analysis of polycyclic aromatic hydrocarbon‐DNA adducts in white blood cells of foundry workers, Journal of Toxicology and Environmental Health, 34:2, 177-185, DOI: 10.1080/15287399109531557 To link to this article: http://dx.doi.org/10.1080/15287399109531557
Published online: 19 Oct 2009.
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Date: 07 November 2015, At: 17:25
POSTLABELING ANALYSIS OF POLYCYCLIC AROMATIC HYDROCARBON-DNA ADDUCTS IN WHITE BLOOD CELLS OF FOUNDRY WORKERS M. Vijayaraj Reddy
Downloaded by [University of Florida] at 17:25 07 November 2015
Department of Pharmacology, Baylor College of Medicine, Houston, Texas Kari Hemminki Institute of Occupational Health, Helsinki, Finland Kurt Randerath Department of Pharmacology, Baylor College of Medicine, Houston, Texas
Blood samples were obtained from 61 volunteers working in a Finnish iron foundry who were exposed to carcinogenic polycyclic aromatic hydrocarbons and from 19 control subjects not known to be exposed to these chemicals. Foundry workers were categorized into high, medium, or low exposure groups, based on their exposure levels to airborne benzo[a]pyrene (BaP) (high >0.2, medium 0.05-0.2, low 0.2 fig BaP/m3), medium (0.05-0.2 fig BaP/m3), and low (