CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2015; 21: 3395-3400 DOI: 10.12659/MSM.894774
Platelet-to-Lymphocyte Ratio May Predict the Severity of Calcific Aortic Stenosis
Received: 2015.05.26 Accepted: 2015.07.20 Published: 2015.11.06
Authors’ ABEF Contribution: Serkan Akdag Study Design A BCF Aytac Akyol Data Collection B BDF Muntecep Asker Statistical Analysis C Data Interpretation BCD D Ramazan Duz Manuscript Preparation E CEF Hasan Ali Gumrukcuoglu Literature Search F Funds Collection G
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Department of Cardiology, Yuzuncu Yil University Medical Faculty, Van, Turkey
Serkan Akdag, e-mail: [email protected] Departmental sources
Platelet-to-lymphocyte ratio (PLR) is an emerging inflammatory indicator which is closely associated with adverse cardiovascular events. Therefore, we aimed to investigate the relationship between PLR and the severity of calcific aortic stenosis (AS). The study was designed as a retrospective study. A total of 86 consecutive patients with calcific AS were divided into two groups as mild-to-moderate AS and severe AS according to the transaortic mean pressure gradient. PLR levels were calculated from the complete blood count (CBC). Platelet to lymphocyte ratio was significantly higher in severe and mild-to-moderate AS groups when compared to the control subjects (151±31.2, p
Platelet-to-Lymphocyte Ratio May Predict the Severity of Calcific Aortic Stenosis
Received: 2015.05.26 Accepted: 2015.07.20 Published: 2015.11.06
Authors’ ABEF Contribution: Serkan Akdag Study Design A BCF Aytac Akyol Data Collection B BDF Muntecep Asker Statistical Analysis C Data Interpretation BCD D Ramazan Duz Manuscript Preparation E CEF Hasan Ali Gumrukcuoglu Literature Search F Funds Collection G
Corresponding Author: Source of support:
Background:
Material/Methods:
Results:
Conclusions:
MeSH Keywords:
Full-text PDF:
Department of Cardiology, Yuzuncu Yil University Medical Faculty, Van, Turkey
Serkan Akdag, e-mail: [email protected] Departmental sources
Platelet-to-lymphocyte ratio (PLR) is an emerging inflammatory indicator which is closely associated with adverse cardiovascular events. Therefore, we aimed to investigate the relationship between PLR and the severity of calcific aortic stenosis (AS). The study was designed as a retrospective study. A total of 86 consecutive patients with calcific AS were divided into two groups as mild-to-moderate AS and severe AS according to the transaortic mean pressure gradient. PLR levels were calculated from the complete blood count (CBC). Platelet to lymphocyte ratio was significantly higher in severe and mild-to-moderate AS groups when compared to the control subjects (151±31.2, p
