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Dentistry (Sunnyvale). Author manuscript; available in PMC 2017 March 08. Published in final edited form as: Dentistry (Sunnyvale). 2016 October ; 6(10): . doi:10.4172/2161-1122.1000396.
Plaque Removal and Gingival Health after Use of a Novel Dental Gel: A Clinical Study Anuradha Nayudu, Tracie Lam, Jessica Ho, Ali Forghany, Thinh Vu, William Ngo, Janet Ajdaharian, and Petra Wilder-Smith* Beckman Laser Institute, University of California, Irvine, CA
Author Manuscript
Abstract Background—Goal of this in vivo prospective, randomized, controlled, double-blinded, cross over study was to compare the level of plaque control and gingivitis after use of a novel dental gel (test) vs. A Triclosan/copolymer dentifrice (control). Methods—After coronal polishing, 22 subjects with moderate gingivitis were randomly assigned to brush twice daily with test or control dentifrice for the first study Arm. Plaque, gingival and sulcus bleeding indices were recorded at baseline, week 2 and week 4. Professional coronal polishing was repeated, and then subjects brushed with the second dentifrice for 4 weeks. Clinical indices were again recorded at Baseline, week 2 and week 4. The effects of each dentifrice on clinical indices were compared using Student’s t-test.
Author Manuscript
Results—Brushing with the test gel produced significantly greater levels of plaque reduction versus the Triclosan/copolymer control dentifrice at each time point. 45% less plaque was measured after 4 weeks of test agent use than after control agent use (p
Dentistry (Sunnyvale). Author manuscript; available in PMC 2017 March 08. Published in final edited form as: Dentistry (Sunnyvale). 2016 October ; 6(10): . doi:10.4172/2161-1122.1000396.
Plaque Removal and Gingival Health after Use of a Novel Dental Gel: A Clinical Study Anuradha Nayudu, Tracie Lam, Jessica Ho, Ali Forghany, Thinh Vu, William Ngo, Janet Ajdaharian, and Petra Wilder-Smith* Beckman Laser Institute, University of California, Irvine, CA
Author Manuscript
Abstract Background—Goal of this in vivo prospective, randomized, controlled, double-blinded, cross over study was to compare the level of plaque control and gingivitis after use of a novel dental gel (test) vs. A Triclosan/copolymer dentifrice (control). Methods—After coronal polishing, 22 subjects with moderate gingivitis were randomly assigned to brush twice daily with test or control dentifrice for the first study Arm. Plaque, gingival and sulcus bleeding indices were recorded at baseline, week 2 and week 4. Professional coronal polishing was repeated, and then subjects brushed with the second dentifrice for 4 weeks. Clinical indices were again recorded at Baseline, week 2 and week 4. The effects of each dentifrice on clinical indices were compared using Student’s t-test.
Author Manuscript
Results—Brushing with the test gel produced significantly greater levels of plaque reduction versus the Triclosan/copolymer control dentifrice at each time point. 45% less plaque was measured after 4 weeks of test agent use than after control agent use (p
