Peripartum Anesthetic Management of a Parturient with Inherited Factor V Deficiency Sonia Vaida, MD, Hamid Al-Mondhiry, MD, Dmitri Bezinover, MD, PhD, Lauren Welsh, MD, Serdar Ural, MD, and Piotr Janicki, MD, PhD Inherited Factor V deficiency is a rare bleeding disorder. We describe the genetic analysis and anesthetic management of a parturient with severe Factor V deficiency who presented in spontaneous labor. Good hemostatic conditions were obtained with prophylactic fresh frozen plasma administration of 10 mL/kg. Detailed genetic analysis by next-generation sequencing identified several relevant mutations in the coding part of the Factor V (F5) gene in our patient, her parents, and the newborn.  (A&A Case Reports 2013;1:86–8)

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nherited coagulation Factor V deficiency, also known as parahemophilia, is a rare bleeding disorder, with a prevalence of