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Sex Transm Dis. Author manuscript; available in PMC 2017 August 01. Published in final edited form as: Sex Transm Dis. 2016 August ; 43(8): 471–475. doi:10.1097/OLQ.0000000000000472.

Perceived Risk Among HIV Serodiscordant Couples in East Africa Taking Oral PrEP Jennifer J. Carrolla,b, Renee Heffrona,c, Nelly Mugog, Kenneth Ngurec,f, Patrick Ndasee, Stephen Asiimweh, Connie Celuma,c,d, and Jared M Baetena,c,d

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aDepartment

of Epidemiology bDepartment of Anthropology, University of Washington, Seattle, Washington, USA cDepartment of Global Health, University of Washington, Seattle, Washington, USA dDepartment of Medicine, University of Washington, Seattle, Washington, USA eInternational Clinical Research Center, University of Washington, Seattle, Washington, USA fJomo Kenyatta University of Agriculture and Technology, Nairobi, Kenya gKenya Medical Research Institute, Nairobi, Kenya hKabwohe Clinical Research Center, Kabwohe, Uganda

Abstract Objectives—Perceived risk of HIV infection is thought to drive low adherence in preexposure prophylaxis (PrEP) trials. We explored the level of perceived risk of incident HIV infection in the Partners PrEP Study, in which adherence was generally high.

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Methods—A cross-sectional questionnaire assessed perceived risk of HIV at 12 months after enrollment. Logistic regression was used to analyze the relationship between perceived risk and other demographic and behavioral variables. Results—3226 couples from the Partners PrEP Study were included in this analysis. Only 15.4% of participants reported high or moderate perceived risk. Participants at high risk of acquiring HIV were slightly more likely to report high perceived risk (OR=1.60, 95%CI: 1.30– 1.95, p

Perceived Risk Among Human Immunodeficiency Virus Serodiscordant Couples in East Africa Taking Oral Pre-Exposure Prophylaxis.

Perceived risk of human immunodeficiency virus (HIV) infection is thought to drive low adherence in pre-exposure prophylaxis (PrEP) trials. We explore...
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