Case Report
Pediatric subacute cutaneous lupus erythematosus: report of three cases Jennifer J. Schoch1, MD, Margot S. Peters1,2, MD, Ann M. Reed3,4, MD, and Megha M. Tollefson1,4, MD
1 Department of Dermatology, Mayo Clinic, Rochester, MN, USA, 2Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA, 3Division of Rheumatology, Mayo Clinic, Rochester, MN, USA, and 4 Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA
Correspondence Megha M. Tollefson, MD Department of Dermatology Mayo Clinic, 200 First St SW, Rochester MN 55905, USA E-mail: [email protected] Portions of this work were previously presented as a poster at the annual meeting of the Society for Pediatric Dermatology, Monterey, CA, July 13, 2012. Conflicts of interest: None.
Pediatric subacute cutaneous lupus erythematosus (SCLE) is a rare entity, with few published cases in the English language literature. We report an additional case, to add to the few available cases. Given the rarity of this diagnosis in children, we also investigated the Mayo Clinic experience with pediatric SCLE. Only two other patients were identified in addition to our index case. Report of a Case An 11-year-old boy presented to our dermatology department (Mayo Clinic, Rochester, MN, USA) with a 3-month history of a rapidly enlarging annular lesion on his left cheek (Fig. 1), followed by development of a lesion in the left postauricular area. The skin lesions had been unresponsive to treatment with topical antifungals and topical corticosteroids. He also received a trial of doxycycline for suspected Lyme disease, despite negative Borrelia serology. After treatment with doxycycline, the rash worsened, and headache, fatigue, and arthralgias developed. Serologic testing revealed: positive antinuclear antibodies (ANAs) (>12.0 U [reference range 8.0 U [reference range 8.0 U [reference range
Pediatric subacute cutaneous lupus erythematosus: report of three cases Jennifer J. Schoch1, MD, Margot S. Peters1,2, MD, Ann M. Reed3,4, MD, and Megha M. Tollefson1,4, MD
1 Department of Dermatology, Mayo Clinic, Rochester, MN, USA, 2Division of Anatomic Pathology, Mayo Clinic, Rochester, MN, USA, 3Division of Rheumatology, Mayo Clinic, Rochester, MN, USA, and 4 Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA
Correspondence Megha M. Tollefson, MD Department of Dermatology Mayo Clinic, 200 First St SW, Rochester MN 55905, USA E-mail: [email protected] Portions of this work were previously presented as a poster at the annual meeting of the Society for Pediatric Dermatology, Monterey, CA, July 13, 2012. Conflicts of interest: None.
Pediatric subacute cutaneous lupus erythematosus (SCLE) is a rare entity, with few published cases in the English language literature. We report an additional case, to add to the few available cases. Given the rarity of this diagnosis in children, we also investigated the Mayo Clinic experience with pediatric SCLE. Only two other patients were identified in addition to our index case. Report of a Case An 11-year-old boy presented to our dermatology department (Mayo Clinic, Rochester, MN, USA) with a 3-month history of a rapidly enlarging annular lesion on his left cheek (Fig. 1), followed by development of a lesion in the left postauricular area. The skin lesions had been unresponsive to treatment with topical antifungals and topical corticosteroids. He also received a trial of doxycycline for suspected Lyme disease, despite negative Borrelia serology. After treatment with doxycycline, the rash worsened, and headache, fatigue, and arthralgias developed. Serologic testing revealed: positive antinuclear antibodies (ANAs) (>12.0 U [reference range 8.0 U [reference range 8.0 U [reference range
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