Rev Bras Cir Cardiovasc 2014;29(3):322-9
Miana LA, etORIGINAL al. - Pediatric and congenital heart transplant: twenty-year ARTICLE experience in a tertiary Brazilian Hospital
Pediatric and congenital heart transplant: twenty-year experience in a tertiary Brazilian Hospital Experiência de 20 anos com transplante cardíaco pediátrico e em portadores de cardiopatias congênitas
Leonardo Augusto Miana1, MD PhD; Estela Azeka2, MD PhD; Luiz Fernando Canêo2, MD PhD; Aída Luisa Turquetto2; Carla Tanamati2, MD PhD; Juliano Gomes Penha2, MD; Alexandre Cauduro2, MD; Marcelo Biscegli Jatene2, MD, MsC, PhD
DOI 10.5935/1678-9741.20140106
RBCCV 44205-1557
Abstract Introduction: Cardiac transplantation remains the gold standard for end-stage cardiomyopathies and congenital heart defects in pediatric patients. Objective: This study aims to report on 20 years of experience since the first case and evaluate our results. Methods: We conducted a retrospective analysis of the database and outpatient follow-up. Between October 1992 and April 2012, 109 patients underwent 114 transplants. 51.8% of them being female. The age of patients ranged from 12 days to 21 years with a mean of 8.8+5.7 years and a median of 5.2 years. The underlying diagnosis was dilated cardiomyopathy in 61.5%, congenital heart disease in 26.6% and restrictive cardiomyopathy in 11.9%. All patients above 17 years old had congenital heart disease. Results: Survival rate at 30 days, 1, 5, 10, 15, and 20 years were 90.4%, 81.3%, 70.9%, 60.5%, 44.4% and 26.7%, respectively. Mean cold ischemic time was 187.9 minutes and it did not correlate with mortality (P>0.05). Infectious complications and rejection episodes were the most common complications
(P0,05). Intercorrências infecciosas e rejeição foram as complicações mais incidentes (P
Miana LA, etORIGINAL al. - Pediatric and congenital heart transplant: twenty-year ARTICLE experience in a tertiary Brazilian Hospital
Pediatric and congenital heart transplant: twenty-year experience in a tertiary Brazilian Hospital Experiência de 20 anos com transplante cardíaco pediátrico e em portadores de cardiopatias congênitas
Leonardo Augusto Miana1, MD PhD; Estela Azeka2, MD PhD; Luiz Fernando Canêo2, MD PhD; Aída Luisa Turquetto2; Carla Tanamati2, MD PhD; Juliano Gomes Penha2, MD; Alexandre Cauduro2, MD; Marcelo Biscegli Jatene2, MD, MsC, PhD
DOI 10.5935/1678-9741.20140106
RBCCV 44205-1557
Abstract Introduction: Cardiac transplantation remains the gold standard for end-stage cardiomyopathies and congenital heart defects in pediatric patients. Objective: This study aims to report on 20 years of experience since the first case and evaluate our results. Methods: We conducted a retrospective analysis of the database and outpatient follow-up. Between October 1992 and April 2012, 109 patients underwent 114 transplants. 51.8% of them being female. The age of patients ranged from 12 days to 21 years with a mean of 8.8+5.7 years and a median of 5.2 years. The underlying diagnosis was dilated cardiomyopathy in 61.5%, congenital heart disease in 26.6% and restrictive cardiomyopathy in 11.9%. All patients above 17 years old had congenital heart disease. Results: Survival rate at 30 days, 1, 5, 10, 15, and 20 years were 90.4%, 81.3%, 70.9%, 60.5%, 44.4% and 26.7%, respectively. Mean cold ischemic time was 187.9 minutes and it did not correlate with mortality (P>0.05). Infectious complications and rejection episodes were the most common complications
(P0,05). Intercorrências infecciosas e rejeição foram as complicações mais incidentes (P
