International Journal of Surgical Pathology http://ijs.sagepub.com/
Papillary Thyroid Microcarcinoma: How to Diagnose It and How to Manage This Epidemics? Paula Soares, Ricardo Celestino, Adriana Gaspar da Rocha and Manuel Sobrinho-Simões INT J SURG PATHOL published online 7 January 2014 DOI: 10.1177/1066896913517394 The online version of this article can be found at: http://ijs.sagepub.com/content/early/2014/01/06/1066896913517394
Published by: http://www.sagepublications.com
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>> OnlineFirst Version of Record - Jan 7, 2014 What is This?
Downloaded from ijs.sagepub.com at Scientific library of Moscow State University on January 22, 2014
517394
research-article2014
IJSXXX10.1177/1066896913517394International Journal of Surgical PathologySoares et al
Original Article
Papillary Thyroid Microcarcinoma: How to Diagnose It and How to Manage This Epidemics?
International Journal of Surgical Pathology 1–7 © The Author(s) 2014 Reprints and permissions: sagepub.com/journalsPermissions.nav DOI: 10.1177/1066896913517394 ijs.sagepub.com
Paula Soares, BSc, PhD1,2, Ricardo Celestino, BSc, PhD1, Adriana Gaspar da Rocha, BSc1,2, and Manuel Sobrinho-Simões, MD, PhD1,2,3
Abstract The incidence of papillary thyroid microcarcinoma (PTmC) has been increasing everywhere due to the improvement of imaging and morphological diagnoses and probably also due to environmental alterations. Despite this, the mortality caused by thyroid cancer has not increased, reflecting the low clinical aggressiveness of most papillary thyroid carcinomas (PTCs) and the quality of the available treatment. The criteria used to classify PTmC remain questionable, making the clinical risk evaluation of these lesions very difficult. There is no solid basis for establishing the most appropriate tumor size (currently
Papillary Thyroid Microcarcinoma: How to Diagnose It and How to Manage This Epidemics? Paula Soares, Ricardo Celestino, Adriana Gaspar da Rocha and Manuel Sobrinho-Simões INT J SURG PATHOL published online 7 January 2014 DOI: 10.1177/1066896913517394 The online version of this article can be found at: http://ijs.sagepub.com/content/early/2014/01/06/1066896913517394
Published by: http://www.sagepublications.com
Additional services and information for International Journal of Surgical Pathology can be found at: Email Alerts: http://ijs.sagepub.com/cgi/alerts Subscriptions: http://ijs.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav
>> OnlineFirst Version of Record - Jan 7, 2014 What is This?
Downloaded from ijs.sagepub.com at Scientific library of Moscow State University on January 22, 2014
517394
research-article2014
IJSXXX10.1177/1066896913517394International Journal of Surgical PathologySoares et al
Original Article
Papillary Thyroid Microcarcinoma: How to Diagnose It and How to Manage This Epidemics?
International Journal of Surgical Pathology 1–7 © The Author(s) 2014 Reprints and permissions: sagepub.com/journalsPermissions.nav DOI: 10.1177/1066896913517394 ijs.sagepub.com
Paula Soares, BSc, PhD1,2, Ricardo Celestino, BSc, PhD1, Adriana Gaspar da Rocha, BSc1,2, and Manuel Sobrinho-Simões, MD, PhD1,2,3
Abstract The incidence of papillary thyroid microcarcinoma (PTmC) has been increasing everywhere due to the improvement of imaging and morphological diagnoses and probably also due to environmental alterations. Despite this, the mortality caused by thyroid cancer has not increased, reflecting the low clinical aggressiveness of most papillary thyroid carcinomas (PTCs) and the quality of the available treatment. The criteria used to classify PTmC remain questionable, making the clinical risk evaluation of these lesions very difficult. There is no solid basis for establishing the most appropriate tumor size (currently
