Outcome of Standard and High-Risk Patients With Acute Anterior Circulation Stroke After Stent Retriever Thrombectomy Pascal P. Gratz, Simon Jung, Gerhard Schroth, Jan Gralla, Pasquale Mordasini, Kety Hsieh, Mirjam R. Heldner, Heinrich P. Mattle, Marie-Luise Mono, Urs Fischer, Marcel Arnold and Christoph Zubler Stroke. 2014;45:152-158; originally published online November 21, 2013; doi: 10.1161/STROKEAHA.113.002591 Stroke is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Copyright © 2013 American Heart Association, Inc. All rights reserved. Print ISSN: 0039-2499. Online ISSN: 1524-4628
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Outcome of Standard and High-Risk Patients With Acute Anterior Circulation Stroke After Stent Retriever Thrombectomy Pascal P. Gratz, MD*; Simon Jung, MD*; Gerhard Schroth, MD; Jan Gralla, MD; Pasquale Mordasini, MD; Kety Hsieh, MD; Mirjam R. Heldner, MD; Heinrich P. Mattle, MD; Marie-Luise Mono, MD; Urs Fischer, MD; Marcel Arnold, MD*; Christoph Zubler, MD* Background and Purpose—Stent retrievers have become an important tool for the treatment of acute ischemic stroke. The aim of this study was to analyze outcome and complications in a large cohort of patients with stroke treated with the Solitaire stent retriever. The study also included patients who did not meet standard inclusion criteria for endovascular treatment: low or high baseline National Institutes of Health Stroke Scale score, ≥80 years of age, extensive ischemic signs in middle cerebral artery territory, and time from symptom onset to endovascular intervention >8 hours. Methods—Consecutive patients with acute anterior circulation stroke treated with the Solitaire FR were analyzed. Data on characteristics of endovascular interventions, complications, and clinical outcome were collected prospectively. Patients who met standard inclusion criteria were compared with those who did not. Results—A total of 227 patients were included. Mean age was 68.2±14.7 years, and median National Institutes of Health Stroke Scale score on admission was 16 (range, 2–36). Reperfusion was successful (thrombolysis in cerebral infarction, 2b–3) in 70.9%. Outcome was favorable (modified Rankin Scale, 0–2) in 57.7% of patients who met standard inclusion criteria and 30.3% of those who did not. The rates for symptomatic intracranial hemorrhage were 3.7% and 13.1%, for death 11.4% and 33.8%, and for symptomatic intraprocedural complications 2.5% and 4.8%, respectively. Conclusions—Patients
The online version of this article, along with updated information and services, is located on the World Wide Web at: http://stroke.ahajournals.org/content/45/1/152
Data Supplement (unedited) at: http://stroke.ahajournals.org/content/suppl/2013/11/21/STROKEAHA.113.002591.DC1.html
Permissions: Requests for permissions to reproduce figures, tables, or portions of articles originally published in Stroke can be obtained via RightsLink, a service of the Copyright Clearance Center, not the Editorial Office. Once the online version of the published article for which permission is being requested is located, click Request Permissions in the middle column of the Web page under Services. Further information about this process is available in the Permissions and Rights Question and Answer document. Reprints: Information about reprints can be found online at: http://www.lww.com/reprints Subscriptions: Information about subscribing to Stroke is online at: http://stroke.ahajournals.org//subscriptions/
Downloaded from http://stroke.ahajournals.org/ at Duke University--Durham on November 11, 2014
Outcome of Standard and High-Risk Patients With Acute Anterior Circulation Stroke After Stent Retriever Thrombectomy Pascal P. Gratz, MD*; Simon Jung, MD*; Gerhard Schroth, MD; Jan Gralla, MD; Pasquale Mordasini, MD; Kety Hsieh, MD; Mirjam R. Heldner, MD; Heinrich P. Mattle, MD; Marie-Luise Mono, MD; Urs Fischer, MD; Marcel Arnold, MD*; Christoph Zubler, MD* Background and Purpose—Stent retrievers have become an important tool for the treatment of acute ischemic stroke. The aim of this study was to analyze outcome and complications in a large cohort of patients with stroke treated with the Solitaire stent retriever. The study also included patients who did not meet standard inclusion criteria for endovascular treatment: low or high baseline National Institutes of Health Stroke Scale score, ≥80 years of age, extensive ischemic signs in middle cerebral artery territory, and time from symptom onset to endovascular intervention >8 hours. Methods—Consecutive patients with acute anterior circulation stroke treated with the Solitaire FR were analyzed. Data on characteristics of endovascular interventions, complications, and clinical outcome were collected prospectively. Patients who met standard inclusion criteria were compared with those who did not. Results—A total of 227 patients were included. Mean age was 68.2±14.7 years, and median National Institutes of Health Stroke Scale score on admission was 16 (range, 2–36). Reperfusion was successful (thrombolysis in cerebral infarction, 2b–3) in 70.9%. Outcome was favorable (modified Rankin Scale, 0–2) in 57.7% of patients who met standard inclusion criteria and 30.3% of those who did not. The rates for symptomatic intracranial hemorrhage were 3.7% and 13.1%, for death 11.4% and 33.8%, and for symptomatic intraprocedural complications 2.5% and 4.8%, respectively. Conclusions—Patients
