Gut, 1990,31: 82-87
82
LIVER, BILIARY, AND PANCREAS
Osteoporosis and skeletal fractures in chronic liver disease T Diamond, D Stiel, M Lunzer, M Wilkinson, J Roche, S Posen
Departments of Endocrinology, Gastroenterology and Radiology, Royal North Shore Hospital, St Leonards, Sydney,
Australia T Diamond D Stiel M Lunzer M Wilkinson J Roche S Posen Correspondence to: Dr T Diamond, Royal North Shore Hospital, St Leonards, NSW,
2065, Australia. Accepted for publication 11 April 1989
Abstract In order to determine the prevalence and severity of hepatic osteodystrophy by noninvasive means we compared 115 consecutive ambulant patients with histologically proven chronic liver disease to 113 age and sex matched control subjects. Methods used included the assessment offracture prevalence rates, spinal radiography, and measurements of bone mineral density in the spine and the forearm. Spinal and peripheral fractures were more prevalent in the patients than in the control subjects (p
82
LIVER, BILIARY, AND PANCREAS
Osteoporosis and skeletal fractures in chronic liver disease T Diamond, D Stiel, M Lunzer, M Wilkinson, J Roche, S Posen
Departments of Endocrinology, Gastroenterology and Radiology, Royal North Shore Hospital, St Leonards, Sydney,
Australia T Diamond D Stiel M Lunzer M Wilkinson J Roche S Posen Correspondence to: Dr T Diamond, Royal North Shore Hospital, St Leonards, NSW,
2065, Australia. Accepted for publication 11 April 1989
Abstract In order to determine the prevalence and severity of hepatic osteodystrophy by noninvasive means we compared 115 consecutive ambulant patients with histologically proven chronic liver disease to 113 age and sex matched control subjects. Methods used included the assessment offracture prevalence rates, spinal radiography, and measurements of bone mineral density in the spine and the forearm. Spinal and peripheral fractures were more prevalent in the patients than in the control subjects (p
