Journal of Cutaneous Pathology 1978: 5: 216-217

Oral eandidiasis A 61-year-old Caucasian female with the tetrad chronic mucocutaneous eandidiasis, myositis, thymoma, and alopecia* consulted because of one of her periodic excacerbations of oral yeast infection. Clinically, there were thiek white patches (Fig. 1) involving about 50% of the surface of the oral mucosa. Histopathologically, a parakeratotie epithelium was heavily invaded by pseudohyphae, blastospores, and cblamydospores of Candida albicans. Tbese features were observed in histological sections and by transmission eleetron microscopy.** Scanning electron microscopy was used to provide new information on the surfaces of the lesions and the two type of microorganistns associated with the surfaces. The larger microorganisms were yeasts, Candida albicans (Ca), whieh penetrated the scale-like epitbelial cells (Fig. 2). The smaller, more numerous microorganisms were bacteria (B) which did not penetrate the cells but remained on the surfaces of the scales(s). Leopoldo F. Montes Laboratory of Dermatopathology Department of Dermatology University of Alabama in Birmingham Medical Center Birmingham, Alabama 35294 U.S.A.

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Walter H. Wilborn Department of Anatomy College of Medicine University of South Alabama Mobile, Alabama 36688 U.S.A.

*Montes, L. F. and Ceballos, R. (1975) Alopeeia Areata. Journal of Cutaneous Pathology 2: 262-263. **Montes, L. F. and Wilbotn, W. H. (1968) Ultrastructural features of host-parasite relationship in oral eandidiasis. Journal of Bacteriology 96: 1349-1356. Studies on eandidiasis are supported by a grant from the John A. Hartford Foundation, Inc.

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ORAL CANDIDIASIS

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Oral candidiasis.

Journal of Cutaneous Pathology 1978: 5: 216-217 Oral eandidiasis A 61-year-old Caucasian female with the tetrad chronic mucocutaneous eandidiasis, my...
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