One-Pot Synthesis of Allylic Sulfones, Ketosulfones, and Trifylallylic Alcohols from Domino Reactions of Allylic Alcohols with Sulfinic Acid under Metal-Free Conditions
Invited for the cover of this issue is the group of Shun-Jun Ji and co-workers at Soochow University, (China). The image depicts a cheaper, low-toxic, eco-friendly benign and metal-free methodology incorporating the both aryl and trifyl sulfonyl functionality from allylic alcohols. Read the full text of the article at 10.1002/chem.201500469.
How would you describe your research? The assembly of important sulfonyl skeletons from widely available allylic alcohols and sulfinic acids through direct Callyl¢S bond formation and iodine(III)-promoted oxidative functionalization was developed. A variety of allylic sulfones, g-keto sulfones, and trifyl allylic alcohols were constructed under metal-free conditions in a single operation. In particular, we can incorporate both the aryl and trifyl sulfonyl functionality, leading to a very powerful and universal tool in synthetic organic chemistry with a very broad scope.
ures and “outstanding” people. The cover illustrates the flexibility of the allylic alcohols and the representative culture of Suzhou. We think the inspiration of the cover owes much to our homeland.
What other topics are you working on at the moment? Beside our research on metal-free sulfonylation reactions, we are always interested in three research fields involving the development of green synthetic approaches, the discovery of highly efficient methods for the synthesis of bioactive molecules, especially those containing heterocyclic skeletons, and the design and synthesis of organic optoelectronic functional materials, as well as their applications in organic light-emitting diodes. Around these three topics, isocyanide-based reaction chemistry has been well developed in our group in recent years, about thirty papers have been published. Our current attention also focuses on the radical addition initiated rearrangement or cyclcization cascade. We hope the diversity of the organic reactions can be fully controlled in the future. It has always been known that only with constant innovation can we have the drive to develop beautiful chemistry.
What was the inspiration for this cover design? When we were invited to submit a cover suggestion, we thought of the main features of the introduced reaction, which is flexible, useful and fascinating. The first thing that came to mind is the city of Suzhou. With 2500 years’ worth of history, Suzhou city is famous for its numerous canals, bridges, Wupeng boats, “nature’s” treasChem. Eur. J. 2015, 21, 11261
Ó 2015 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim