ON THE NATURE AND PHYSIOLOGICAL ACTION OF THE POISON OP NAJA TIIIPUDIANS AND OTHER INDIAN VENOMOUS SNAKES. By T. Ladder Brdnton, M.D., Sc. D., M.R.C.P., and j. Fayrer, I M.D., F.ll.C.P., Lond , F.R.S.E.,

[From

the

Surgeon-Major, Bengal Army. Proceedings of the Royal Society, No. 149,1874.] On the Poison of Naja tripudians. (Concluded from page 279J.

Experiment LXIX. June 26, 1872.?Half a drop of cobra-poison diluted with ? cub. centim. of water was injected under the skin of a guineapig, weighing about 450 grammes (1 tl5.). At 12.13.15 the injection was made. Immediately the animal became restless and cried constantly. At 12.15 twitching movements began in the limbs. At 12.16 the animal was quiet, and would not move when It then became restless again, and remained so touched. till 12,44. 12.44. The jugular vein was exposed, and ? cub. centim. of the diluted poison was injected into it (== ? drop of poison). In less than 30 seconds the animal appeared to be dead. The thorax was opened, and the heart found to be motionless, and the walls of all its cavities firmly contracted. The were

lungs

ecchymosed.

inserted into the spinal cord, and an interrupted current passed through it. Whenever the current passed, the legs of the animal jerked vigorously. The blood which was collected from the large thoracic vessels formed a firm congulum. 1,22. The cord was still irritable when excited by the induced current. Experiment LXX. 12.55.

Electrodes

wero

Jan. 14, 1873.?The heart of a frog was excised. It beat Several drops of cobra-poison were then 20 times in 1 minute. placed upon it, and it beat 24 times in 1 itminute. When seized stopped in systole; with forceps and placed in cobra-poison but this might be due to the effect of the compression by the

forceps.

Experiment LXXI. Beats, 30 in the first

heart excised. the second.

Frog's

minute,

34 in

Cobra-poison applied to it. It immediately stopped, and began again, but slowly and feebly. Then it beat 26 times per minute, less strongly than before. It gradually recovered and seemed little affected, but stopped about 10 or 15 minutes then

afterwards.

THE INDIAN MEDICAL GAZETTE.

304

Experiment LXXII. A cannula was placed in the aorta, and another in the vena All branches were tie

On the Nature and Physiological Action of the Poison of Naja Tripudians and Other Indian Venomous Snakes.

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