original article
Obesity and chronic obstructive pulmonary disease: Is fatter really better? Roxana G Galesanu MD MSc1, Sarah Bernard MSc1, Karine Marquis PhD1, Yves Lacasse MD MSc1, Paul Poirier MD PhD1, Jean Bourbeau MD MSc2, François Maltais MD1 RG Galesanu, S Bernard, K Marquis, et al. Obesity and chronic obstructive pulmonary disease: Is fatter really better? Can Respir J 2014;21(5):297-301. Background: Overweight/obesity is associated with longer survival in chronically ill patients, a phenomenon referred to as the ‘obesity paradox’. Objective: To investigate whether the obesity paradox in patients with chronic obstructive pulmonary disease (COPD) is due to fat accumulation or confounding factors. Methods: A total of 190 patients with stable COPD who underwent a mean (± SD) follow-up period of 72±34 months were enrolled. Anthropometry, pulmonary function tests, midthigh muscle cross-sectional area obtained using computed tomography (MTCSACT), arterial blood gas and exercise testing data were measured at baseline. Patients were categorized into two subgroups according to body mass index (BMI)
Obesity and chronic obstructive pulmonary disease: Is fatter really better? Roxana G Galesanu MD MSc1, Sarah Bernard MSc1, Karine Marquis PhD1, Yves Lacasse MD MSc1, Paul Poirier MD PhD1, Jean Bourbeau MD MSc2, François Maltais MD1 RG Galesanu, S Bernard, K Marquis, et al. Obesity and chronic obstructive pulmonary disease: Is fatter really better? Can Respir J 2014;21(5):297-301. Background: Overweight/obesity is associated with longer survival in chronically ill patients, a phenomenon referred to as the ‘obesity paradox’. Objective: To investigate whether the obesity paradox in patients with chronic obstructive pulmonary disease (COPD) is due to fat accumulation or confounding factors. Methods: A total of 190 patients with stable COPD who underwent a mean (± SD) follow-up period of 72±34 months were enrolled. Anthropometry, pulmonary function tests, midthigh muscle cross-sectional area obtained using computed tomography (MTCSACT), arterial blood gas and exercise testing data were measured at baseline. Patients were categorized into two subgroups according to body mass index (BMI)
