CLINICAL RESEARCH e-ISSN 1643-3750 © Med Sci Monit, 2013; 19: 1043-1049 DOI: 10.12659/MSM.884027
Body weight gain and serum leptin levels of non-overweight and overweight/obese pregnant women
Received: 2012.05.19 Accepted: 2013.08.05 Published: 2013.11.22
Authors’ Contribution: Study Design A Data Collection B Analysis C Statistical Data Interpretation D Manuscript Preparation E Literature Search F Collection G Funds
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Didier Silveira Castellano Filho José Otávio do Amaral Correa Plínio dos Santos Ramos Marina de Oliveira Montessi Beatriz Julião Vieira Aarestrup Fernando Monteiro Aarestrup
1 Department of Obstetrics and Gynecology, Therezinha de Jesus Hospital, Faculty of Medical and Health Sciences of Juiz de Fora – SUPREMA, Juiz de Fora, Minas Gerais, Brazil 2 Laboratory of Immunopathology and Experimental Pathology, Center for Reproductive Biology – CRB, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil
Didier Silveira Castellano Filho, e-mail:
[email protected] Departmental funds
Our objective was to evaluate changes in serum leptin levels during pregnancy in overweight/obese and nonobese women and to assess total and percent weight gain during pregnancy as possible factors that influence leptin levels. In a prospective study of 42 low-risk pregnant women receiving prenatal care, we assessed serum leptin levels at gestational weeks 9–12, 25–28, and 34–37. Based on their pre-pregnancy body mass indices (BMIs), the cohort was divided into: non-overweight (BMI