Accepted Manuscript Non-atherosclerotic coronary artery disease in young women Jacqueline Saw, MD Eve Aymong, MD G.B. John Mancini, MD Tara Sedlak, MD Andrew Starovoytov, MD Donald Ricci, MD PII:
S0828-282X(14)00042-7
DOI:
10.1016/j.cjca.2014.01.011
Reference:
CJCA 1100
To appear in:
Canadian Journal of Cardiology
Received Date: 27 September 2013 Revised Date:
16 January 2014
Accepted Date: 16 January 2014
Please cite this article as: Saw J, Aymong E, Mancini GBJ, Sedlak T, Starovoytov A, Ricci D, Nonatherosclerotic coronary artery disease in young women, Canadian Journal of Cardiology (2014), doi: 10.1016/j.cjca.2014.01.011. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
ACCEPTED MANUSCRIPT
Non-atherosclerotic coronary artery disease in young women
Starovoytov, MD, Donald Ricci, MD
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Jacqueline Saw, MD, Eve Aymong, MD, G.B. John Mancini, MD, Tara Sedlak, MD, Andrew
Vancouver General Hospital, Division of Cardiology, Department of Medicine, University of
Address for Correspondence:
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British Columbia, Vancouver, BC, Canada
Jacqueline Saw, MD, FRCPC, FACC, FSCAI
Clinical Associate Professor, UBC
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Vancouver General Hospital 2775 Laurel Street, Level 9, Vancouver, BC, V5Z1M9 Tel: (604) 875 5547 Fax: (604) 875 5563
[email protected] ACCEPTED MANUSCRIPT
BRIEF SUMMARY
Non-atherosclerotic CAD (NACAD) is an important cause of myocardial infarction (MI) in
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young women but is often missed on coronary angiography, especially spontaneous coronary artery dissection (SCAD). We retrospectively reviewed all coronary angiograms of women aged ≤50 at Vancouver General Hospital over 2 years. NACAD was not rare among young women
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encountered NACAD in young women causing 24% of MI.
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and was an important cause of MI accounting for 30%. SCAD was the most commonly
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ABSTRACT
Background: Non-atherosclerotic CAD (NACAD) is an important cause of myocardial infarction
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(MI) in young women but is often missed on coronary angiography, especially spontaneous coronary artery dissection (SCAD). The prevalence of NACAD in young women has not been described.
Methods: We retrospectively reviewed all coronary angiograms of women aged ≤50 at
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Vancouver General Hospital from 12/1/2009 to 11/30/2011. The angiograms were reviewed by 2 experienced interventional cardiologists, and reported as normal (