Original Article

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Nil-Per-Os Days and Necrotizing Enterocolitis in Extremely Preterm Infants Maksim Kirtsman, MDCM, FRCPC, FAAP1 Eugene W. Yoon, MSc1,2 Cecil Ojah, MD, FRCPC3 Zenon Cieslak, MD, FRCPC4 Shoo K. Lee, MBBS, FRCPC, PhD1,2 Prakesh S. Shah, MD, FRCPC, MSc1,2,
1 Department of Pediatrics, Mount Sinai Hospital, University of

Toronto, Toronto, Ontario, Canada 2 Maternal-Infant Care Research Centre, Mount Sinai Hospital, Toronto, Ontario, Canada 3 Department of Pediatrics, Saint John Regional Hospital, Saint John, New Brunswick, Canada 4 Department of Pediatrics, Royal Columbian Hospital, New Westminster, British Columbia, Canada

Address for correspondence Prakesh S. Shah, MD, FRCPC, MSc, Department of Pediatrics, Mount Sinai Hospital, Rm 19-231F, 600 University Avenue, Toronto, ON M5G 1X5, Canada (e-mail: [email protected]).

Abstract

Keywords

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enteral nutrition gut colonization infant premature intestinal microbiome

Objective This study aims to evaluate the association between nil-per-os (NPO) days and development of necrotizing enterocolitis (NEC) in extremely preterm neonates (