Clin. exp. Immunol. (1990) 81, 218-224
Natural killer cell activity during measles D. E. GRIFFIN*t, B. J. WARD*, E. JAUREGUII, R. T. JOHNSONt & A. VAISBERG§ Departments of *Medicine and tNeurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA, National Institute of Child Health, Lima, and §Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, Peru
(Accepted for publication
13
February 1990)
SUMMARY Natural killer cells are postulated to play important role in host anti-viral defences. We measured natural killer cell activity in 30 individuals with acute measles (73 + 21 lytic units (LU)/107 cells) and 16 individuals with other infectious diseases (149+95 LU) and found it reduced compared with values for adults (375 + 70 LU; P
Natural killer cell activity during measles D. E. GRIFFIN*t, B. J. WARD*, E. JAUREGUII, R. T. JOHNSONt & A. VAISBERG§ Departments of *Medicine and tNeurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA, National Institute of Child Health, Lima, and §Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, Peru
(Accepted for publication
13
February 1990)
SUMMARY Natural killer cells are postulated to play important role in host anti-viral defences. We measured natural killer cell activity in 30 individuals with acute measles (73 + 21 lytic units (LU)/107 cells) and 16 individuals with other infectious diseases (149+95 LU) and found it reduced compared with values for adults (375 + 70 LU; P
