Myofascial Pain Syndrome after Head and Neck Cancer Treatment: Prevalence, Risk Factors and Influence on Quality of Life Leticia Rodrigues Cardoso, MSc1; Cláudia Carvalho Rizzo, MD, PhD2; Cleyton Zanardo de Oliveira, MSc3; Carlos Roberto dos Santos, MD4; André Lopes Carvalho, MD, PhD4 Affiliations: 1. Physical Therapy Department, Barretos Cancer Hospital, Barretos, Sao Paulo, Brazil 2. Anesthesiology Department, Barretos Cancer Hospital, Barretos, Sao Paulo, Brazil 3. Biostatistics Department, Barretos Cancer Hospital, Barretos, Sao Paulo, Brazil 4. Head and Neck Surgery Department, Barretos Cancer Hospital, Barretos, Sao Paulo, Brazil Funding: This work was funded by an Internal Institutional grant from Barretos Cancer Hospital. Acknowledgements: We would like to acknowledge the Teaching and Research Institute of the Barretos Cancer Hospital, notably the Centre for Researcher Support, the Post‐Graduate Secretariat and the librarians for support and help in the development of this study. Corresponding Author: Leticia Rodrigues Cardoso, MSc, Physical Therapy Department, Barretos Cancer Hospital, Barretos, Sao Paulo, Brazil, Antenor Duarte Villela Street, n 1331, Zip Code 14784‐ 400 (
[email protected]) Running Title: Myofascial Pain Syndrome after Head and Neck Cancer Treatment Keywords: head and neck cancer, pain, myofascial pain, physiotherapy, quality of life.
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as an ‘Accepted Article’, doi: 10.1002/hed.23825
Abstract Background: Patients undergoing treatment for head and neck cancer (HNC) might develop myofascial pain syndrome (MPS) as sequelae. The aim of this study was to determine the prevalence, risk factors and quality of life related to MPS. Methods: This is a prospective study including HNC patients with at least one year disease free interval. Results: 167 patients were analysed, MPS was diagnosed in 20 (11.9 %). In the multivariate analysis, hypopharynx tumors (OR = 6.35; 95% CI [1.58; 25.56]) and neck dissection (OR = 3.43; 95% CI [1.16; 10.17]) were independent factors for MPS. The pain (p