Original Research published: 28 July 2017 doi: 10.3389/fneur.2017.00365
Midterm Blood Pressure Variability is associated with Poststroke cognitive impairment: a Prospective cohort study Shan Geng, Na Liu, Pin Meng, Niu Ji, Yong’an Sun, Yingda Xu, Guanghui Zhang, Xiaobing He, Zenglin Cai, Bei Wang, Bei Xu, Zaipo Li, Xiaoqin Niu, Yongjin Zhang, Bingchao Xu, Xinyu Zhou and Mingli He* Department of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, China
Objective: The aim of this study was to investigate the relationship between blood pressure variability (BPV) and poststroke cognitive impairment (PSCI). Edited by: Brian Silver, University of Massachusetts Medical School, United States Reviewed by: Loes C. A. Rutten-Jacobs, University of Cambridge, United Kingdom Terence J. Quinn, University of Glasgow, United Kingdom *Correspondence: Mingli He [email protected] Specialty section: This article was submitted to Stroke, a section of the journal Frontiers in Neurology Received: 20 April 2017 Accepted: 11 July 2017 Published: 28 July 2017 Citation: Geng S, Liu N, Meng P, Ji N, Sun Y, Xu Y, Zhang G, He X, Cai Z, Wang B, Xu B, Li Z, Niu X, Zhang Y, Xu B, Zhou X and He M (2017) Midterm Blood Pressure Variability Is Associated with Poststroke Cognitive Impairment: A Prospective Cohort Study. Front. Neurol. 8:365. doi: 10.3389/fneur.2017.00365
Frontiers in Neurology | www.frontiersin.org
Methods: Seven-hundred ninety-six patients with acute ischemic stroke were included in this study. Midterm BPV was evaluated by calculating the SD and coefficient of variation (CV, 100 × SD/mean) of systolic blood pressure (SBP) and diastolic blood pressure during the 7 days after stroke onset. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) at admission and at all follow-up visits. Patients with MoCA scores 1 before stroke onset (no patients); severe mental disorder or dementia (7 patients); serious systemic diseases or expected life span 2.0, which is at the upper limit of normal, or severe liver disease (23 patients); estimated glomerular filtration rate
Midterm Blood Pressure Variability is associated with Poststroke cognitive impairment: a Prospective cohort study Shan Geng, Na Liu, Pin Meng, Niu Ji, Yong’an Sun, Yingda Xu, Guanghui Zhang, Xiaobing He, Zenglin Cai, Bei Wang, Bei Xu, Zaipo Li, Xiaoqin Niu, Yongjin Zhang, Bingchao Xu, Xinyu Zhou and Mingli He* Department of Neurology, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, China
Objective: The aim of this study was to investigate the relationship between blood pressure variability (BPV) and poststroke cognitive impairment (PSCI). Edited by: Brian Silver, University of Massachusetts Medical School, United States Reviewed by: Loes C. A. Rutten-Jacobs, University of Cambridge, United Kingdom Terence J. Quinn, University of Glasgow, United Kingdom *Correspondence: Mingli He [email protected] Specialty section: This article was submitted to Stroke, a section of the journal Frontiers in Neurology Received: 20 April 2017 Accepted: 11 July 2017 Published: 28 July 2017 Citation: Geng S, Liu N, Meng P, Ji N, Sun Y, Xu Y, Zhang G, He X, Cai Z, Wang B, Xu B, Li Z, Niu X, Zhang Y, Xu B, Zhou X and He M (2017) Midterm Blood Pressure Variability Is Associated with Poststroke Cognitive Impairment: A Prospective Cohort Study. Front. Neurol. 8:365. doi: 10.3389/fneur.2017.00365
Frontiers in Neurology | www.frontiersin.org
Methods: Seven-hundred ninety-six patients with acute ischemic stroke were included in this study. Midterm BPV was evaluated by calculating the SD and coefficient of variation (CV, 100 × SD/mean) of systolic blood pressure (SBP) and diastolic blood pressure during the 7 days after stroke onset. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) at admission and at all follow-up visits. Patients with MoCA scores 1 before stroke onset (no patients); severe mental disorder or dementia (7 patients); serious systemic diseases or expected life span 2.0, which is at the upper limit of normal, or severe liver disease (23 patients); estimated glomerular filtration rate
