Signature: © Pol J Radiol, 2015; 80: 536-543 DOI: 10.12659/PJR.895396
ORIGINAL ARTICLE
Received: 2015.07.20 Accepted: 2015.07.27 Published: 2015.12.13
Microvascular Obstruction Evaluation Using Cardiovascular Magnetic Resonance (CMR) in ST-Elevated Myocardial Infarction (STEMI) Patients
Authors’ Contribution: A Study Design B Data Collection C Statistical Analysis D Data Interpretation E Manuscript Preparation F Literature Search G Funds Collection
Dorota Piotrowska-Kownacka1 ABCDEF, Łukasz Kownacki2 ABDE, Janusz Kochman3 BD, Agnieszka Kołodzińska3 BD, Małgorzata Kobylecka4 EF, Leszek Królicki4 AEF 1 1st Department of Radiology, Medical University of Warsaw, Warsaw, Poland 2 Department of Radiology, European Health Center, Otwock, Poland
3 Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
4 Department of Nuclear Medicine, Medical University of Warsaw, Warsaw, Poland
Author’s address: Dorota Piotrowska-Kownacka, 1st Department of Radiology, Medical University of Warsaw, Warsaw, Poland, e-mail: [email protected] Source of support: The study was supported by grant N402 043 32/1326
Summary Backround:
Restoration of blood flow in epicardial coronary artery in patients with acute myocardial infarction can, but does not have to restore efficient blood flow in coronary circulation.
The aim of the study was a direct comparison of microvascular obstruction (MVO) detected by rest and stress perfusion imaging and gadolinium enhancement obtained 2 min. (early MVO) and 15 min. (delayed MVO) post contrast.
Material/Methods:
106 patients with first anterior myocardial infarction were studied. Cardiovascular magnetic resonance (CMR) was performed 5±2 days after primary percutaneous coronary intervention (pPCI). Stress and rest perfusion imaging was performed as well as early and delayed gadolinium enhancement and systolic function assessment.
Scoring of segmental function, perfusion defect, MVO and scar transmurality was performed in 16 segment left ventricular model.
Results:
The prevalence of MVO varies significantly between imaging techniques ranging from 48.8% for delayed MVO to 94% with stress perfusion. Median sum of scores was significantly different for each technique: stress perfusion 13 (7; 18), rest perfusion 3 (0.5; 6), early MVO 3 (0; 8), delayed MVO 0 (0; 4); p
ORIGINAL ARTICLE
Received: 2015.07.20 Accepted: 2015.07.27 Published: 2015.12.13
Microvascular Obstruction Evaluation Using Cardiovascular Magnetic Resonance (CMR) in ST-Elevated Myocardial Infarction (STEMI) Patients
Authors’ Contribution: A Study Design B Data Collection C Statistical Analysis D Data Interpretation E Manuscript Preparation F Literature Search G Funds Collection
Dorota Piotrowska-Kownacka1 ABCDEF, Łukasz Kownacki2 ABDE, Janusz Kochman3 BD, Agnieszka Kołodzińska3 BD, Małgorzata Kobylecka4 EF, Leszek Królicki4 AEF 1 1st Department of Radiology, Medical University of Warsaw, Warsaw, Poland 2 Department of Radiology, European Health Center, Otwock, Poland
3 Department of Cardiology, Medical University of Warsaw, Warsaw, Poland
4 Department of Nuclear Medicine, Medical University of Warsaw, Warsaw, Poland
Author’s address: Dorota Piotrowska-Kownacka, 1st Department of Radiology, Medical University of Warsaw, Warsaw, Poland, e-mail: [email protected] Source of support: The study was supported by grant N402 043 32/1326
Summary Backround:
Restoration of blood flow in epicardial coronary artery in patients with acute myocardial infarction can, but does not have to restore efficient blood flow in coronary circulation.
The aim of the study was a direct comparison of microvascular obstruction (MVO) detected by rest and stress perfusion imaging and gadolinium enhancement obtained 2 min. (early MVO) and 15 min. (delayed MVO) post contrast.
Material/Methods:
106 patients with first anterior myocardial infarction were studied. Cardiovascular magnetic resonance (CMR) was performed 5±2 days after primary percutaneous coronary intervention (pPCI). Stress and rest perfusion imaging was performed as well as early and delayed gadolinium enhancement and systolic function assessment.
Scoring of segmental function, perfusion defect, MVO and scar transmurality was performed in 16 segment left ventricular model.
Results:
The prevalence of MVO varies significantly between imaging techniques ranging from 48.8% for delayed MVO to 94% with stress perfusion. Median sum of scores was significantly different for each technique: stress perfusion 13 (7; 18), rest perfusion 3 (0.5; 6), early MVO 3 (0; 8), delayed MVO 0 (0; 4); p
