MicroReview Microbial pathogenesis and tyrosine dephosphorylation: surprising bedfellows' J. C-Clemens.'K. Guan.'J. B-Biiska,^ S. Falkow'

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Summary

Introduction lyro?in!; pno^'phoiyUiUon-d(^pbospi'io:y!:!!ioii l^as '^o! bi->oii ^u^-ptn'-dod d-s a fePiUiu'' of insctob'ai pa'hogt'nes'S Yci iv'OSinp p'!os;andtase adivify plays a key ''O'e H' Iho virjlencP oi nujmbu's of Ww; gr^nuS Yor-trn.} which !'u:iu(!os !fie b:iC!enij!i'-psponsibis^ for buburiic f)iHgn(j. To uPfU'istand fb.e seial.opsbip bPtw^-^esi (bo pdihoger(.•sir o' Yi-:i-i!!!ci arid tyrossne pliosphoryiaiion and dcfiiosf^boiyianop, w*- wiii first aclosesy t^'r iiorrnai Sunc iiOM of ibi.s pos! tfans^atiopai evepi IP t'uKaiyo^iC cfills Wo will \be'i *!';p!O!i'; IC'CIKM f^ncisngs flx-s; rolnff' to oia updfM sianOinq o' lyrus^in; npphosplioiy^nhon Tiiecliated by pdiiiogi-'iik: bacteiia ana pa'tiogynu- virur.Bs. Ifas snorf !('!v:ew caianor ,i(1'-)qja!f-'ly pxaniuio H'^be' bac(oria^ pa!noQiait'si^; Of tiie-eguialoiy w e p t s asi^oc.auod A'ith tyrosine knuiia'G 0' fi'ic-M^hab'tSi^is (l"ie rpadci is fj.'fcn'ed \o a nuail>oi of oSbiM ; rt^cles o;' PUJSC SjbKHis i,Ak;:'arider 19'JO lonks aod CbaibOPP'arin. ' 0 8 9 Miilpr r / , J / . 1989, (,Oirh"!hs (^' - t , t

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