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Methodological implications in pH standardization of exhaled breath condensate
This content has been downloaded from IOPscience. Please scroll down to see the full text. 2015 J. Breath Res. 9 036003 (http://iopscience.iop.org/1752-7163/9/3/036003) View the table of contents for this issue, or go to the journal homepage for more
Download details: IP Address: 144.32.128.70 This content was downloaded on 07/07/2015 at 08:52
Please note that terms and conditions apply.
J. Breath Res. 9 (2015) 036003
doi:10.1088/1752-7155/9/3/036003
Paper
received
25 November 2014
Methodological implications in pH standardization of exhaled breath condensate
re vised
12 February 2015 accep ted for publication
16 March 2015 published
14 May 2015
F Hoffmeyer, H Berresheim, A Beine, K Sucker, T Brüning and J Bünger Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA), Bochum, Germany E-mail: [email protected] Keywords: exhaled breath condensate, acid-base balance, carbon dioxide, pH
Abstract The variable amount of dissolved carbon dioxide is one of the main confounding factors of exhaled breath condensate (EBC) pH measurements. There have been many attempts at identifying the optimal approach to displace CO2 as a way to gain reproducible and valid pH values in EBC samples. The aim of the present study was to assess the correlation of pH and pCO2 in untreated, neat EBC samples and, after deaeration, to reevaluate the standardization of CO2 as a means to obtain valid pH values. A further aim was to evaluate the impact of deaeration on the acid–base balance in EBC samples. EBC was collected from seven female and 31 male subjects. The pH and pCO2 values immediately determined in untreated, neat EBC samples were strongly correlated (rp = −0.723, p
Search
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My IOPscience
Methodological implications in pH standardization of exhaled breath condensate
This content has been downloaded from IOPscience. Please scroll down to see the full text. 2015 J. Breath Res. 9 036003 (http://iopscience.iop.org/1752-7163/9/3/036003) View the table of contents for this issue, or go to the journal homepage for more
Download details: IP Address: 144.32.128.70 This content was downloaded on 07/07/2015 at 08:52
Please note that terms and conditions apply.
J. Breath Res. 9 (2015) 036003
doi:10.1088/1752-7155/9/3/036003
Paper
received
25 November 2014
Methodological implications in pH standardization of exhaled breath condensate
re vised
12 February 2015 accep ted for publication
16 March 2015 published
14 May 2015
F Hoffmeyer, H Berresheim, A Beine, K Sucker, T Brüning and J Bünger Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr-University Bochum (IPA), Bochum, Germany E-mail: [email protected] Keywords: exhaled breath condensate, acid-base balance, carbon dioxide, pH
Abstract The variable amount of dissolved carbon dioxide is one of the main confounding factors of exhaled breath condensate (EBC) pH measurements. There have been many attempts at identifying the optimal approach to displace CO2 as a way to gain reproducible and valid pH values in EBC samples. The aim of the present study was to assess the correlation of pH and pCO2 in untreated, neat EBC samples and, after deaeration, to reevaluate the standardization of CO2 as a means to obtain valid pH values. A further aim was to evaluate the impact of deaeration on the acid–base balance in EBC samples. EBC was collected from seven female and 31 male subjects. The pH and pCO2 values immediately determined in untreated, neat EBC samples were strongly correlated (rp = −0.723, p
