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CMAJ

Metformin and low levels of thyroid-stimulating hormone in patients with type 2 diabetes mellitus Jean-Pascal Fournier MD PhD, Hui Yin MSc, Oriana Hoi Yun Yu MD MSc, Laurent Azoulay PhD Competing interests: None declared. This article has been peer reviewed. Correspondence to: Laurent Azoulay, [email protected] CMAJ 2014. DOI:10.1503​ /cmaj.140688

Abstract Background: Small cross-sectional studies have suggested that metformin, a first-line oral hypoglycemic agent, may lower thyroid-stimulating hormone (TSH) levels. Our objective was to determine whether the use of metformin monotherapy, when compared with sulfonylurea monotherapy, is associated with an increased risk of low TSH levels (

Metformin and low levels of thyroid-stimulating hormone in patients with type 2 diabetes mellitus.

Small cross-sectional studies have suggested that metformin, a first-line oral hypoglycemic agent, may lower thyroid-stimulating hormone (TSH) levels...
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