RESEARCH ARTICLE

Medical Procedures and Outcomes of Japanese Patients With Trisomy 18 or Trisomy 13: Analysis of a Nationwide Administrative Database of Hospitalized Patients Kazue Ishitsuka,1 Hiroki Matsui,2 Nobuaki Michihata,2 Kiyohide Fushimi,3 Tomoo Nakamura,1 and Hideo Yasunaga2* 1

Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, Japan

2

Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Tokyo, Japan

3

Department of Health Policy and Informatics, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan

Manuscript Received: 7 August 2014; Manuscript Accepted: 12 March 2015

The choices of aggressive treatment for trisomy 18 (T18) and trisomy 13 (T13) remain controversial. Here, we describe the current medical procedures and outcomes of patients with T18 and T13 from a nationwide administrative database of hospitalized patients in Japan. We used the database to identify eligible patients with T18 (n ¼ 438) and T13 (n ¼ 133) who were first admitted to one of 200 hospitals between July 2010 and March 2013. Patients were divided into admission at day