Graefes Arch Clin Exp Ophthalmol (2014) 252:1653–1660 DOI 10.1007/s00417-014-2773-5
NEUROPHTHALMOLOGY
Measurement of retinal nerve fiber layer and macular ganglion cell–inner plexiform layer with spectral-domain optical coherence tomography in patients with optic nerve head drusen Alfonso Casado & Gema Rebolleda & Laura Guerrero & Marina Leal & Inés Contreras & Noelia Oblanca & Francisco J. Muñoz-Negrete
Received: 20 November 2013 / Revised: 11 July 2014 / Accepted: 6 August 2014 / Published online: 17 August 2014 # Springer-Verlag Berlin Heidelberg 2014
Abstract Purpose To evaluate the effect of optic nerve head drusen (ONHD) on the retinal nerve fiber layer (RNFL) and macular ganglion cell–inner plexiform layer (GCIPL) using Cirrus optical coherence tomography (OCT). Methods Fifty-seven eyes of thirty patients with ONHD and thirty-eight eyes of twenty age-matched and sex-matched control subjects underwent circumpapillary and macular scanning using Cirrus OCT. The percentages of eyes with abnormal GCIPL and RNFL values according to the Cirrus normative data were analysed and compared. Results Overall, eyes with ONHD showed abnormally reduced values for average and minimum GCIPL thicknesses in 35 % and 45 % of cases compared to 2 % for both values in control eyes (P
NEUROPHTHALMOLOGY
Measurement of retinal nerve fiber layer and macular ganglion cell–inner plexiform layer with spectral-domain optical coherence tomography in patients with optic nerve head drusen Alfonso Casado & Gema Rebolleda & Laura Guerrero & Marina Leal & Inés Contreras & Noelia Oblanca & Francisco J. Muñoz-Negrete
Received: 20 November 2013 / Revised: 11 July 2014 / Accepted: 6 August 2014 / Published online: 17 August 2014 # Springer-Verlag Berlin Heidelberg 2014
Abstract Purpose To evaluate the effect of optic nerve head drusen (ONHD) on the retinal nerve fiber layer (RNFL) and macular ganglion cell–inner plexiform layer (GCIPL) using Cirrus optical coherence tomography (OCT). Methods Fifty-seven eyes of thirty patients with ONHD and thirty-eight eyes of twenty age-matched and sex-matched control subjects underwent circumpapillary and macular scanning using Cirrus OCT. The percentages of eyes with abnormal GCIPL and RNFL values according to the Cirrus normative data were analysed and compared. Results Overall, eyes with ONHD showed abnormally reduced values for average and minimum GCIPL thicknesses in 35 % and 45 % of cases compared to 2 % for both values in control eyes (P
