Measurement of C A I 25, Carcinoembryonic Antigen, and Alpha-Fetoprotein in Ovarian Cyst Fluid: Diagnostic Adjunct to Cytology Marguerite M. Pinto, M.D., F.I.A.c., Larry H. Bernstein, M.D., Dennis A. Brogan, M.P.H., Firuza Parikh, M.D., and Gaby Lavy, M.D.
This study used CA125,carcinoembryonic antigen (CEA).and alpha-fetoprotein (AFP)to classify ovarian cysts by measuring the levels of the three antigens; this information was useful when fluid obtained through laparoscopic puncture of ovarian cysts was submitted f o r cytologic examination f r o m patients f o r whom tissue was unavailable f o r classification. We studied 136 consecutive cyst fluids (108 benign, 28 malignant) and correlated the findings with the tissue diagnosis. All three antigens were very low (CEA,t0.5 ng/ml; CAI 25, .55-2,143 F/ml; and AFP,
This study used CA125,carcinoembryonic antigen (CEA).and alpha-fetoprotein (AFP)to classify ovarian cysts by measuring the levels of the three antigens; this information was useful when fluid obtained through laparoscopic puncture of ovarian cysts was submitted f o r cytologic examination f r o m patients f o r whom tissue was unavailable f o r classification. We studied 136 consecutive cyst fluids (108 benign, 28 malignant) and correlated the findings with the tissue diagnosis. All three antigens were very low (CEA,t0.5 ng/ml; CAI 25, .55-2,143 F/ml; and AFP,
