ONCOLOGY LETTERS 12: 2501-2506, 2016

Mean platelet volume provides beneficial diagnostic and prognostic information for patients with resectable gastric cancer XIAO-MING SHEN1*, YOU-YOU XIA2,3*, LIAN LIAN1,4*, CHONG ZHOU5, XIANG-LI LI6, SHU-GUANG HAN6, YAN ZHENG1, FEI-RAN GONG7, MIN TAO4,8-10, ZHONG-QI MAO11 and WEI LI4,8,10 1

Department of Oncology, Suzhou Xiangcheng People's Hospital, Suzhou; 2Department of Radiation Oncology, Lianyungang First People's Hospital, Lianyungang; 3The Fourth Clinical Medical College, Nanjing Medical University, Nanjing; 4Department of Oncology, The First Affiliated Hospital of Soochow University, Suzhou; 5Department of Radiation Oncology, Xuzhou Central Hospital, Xuzhou; 6Department of General Surgery, Suzhou Xiangcheng People's Hospital; 7Department of Hematology, The First Affiliated Hospital of Soochow University; 8Jiangsu Institute of Clinical Immunology; 9Institute of Medical Biotechnology, Soochow University; 10PREMED Key Laboratory for Precision Medicine, Soochow University; 11Department of Minimally Invasive Surgery, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, P.R. China Received January 5, 2016; Accepted July 26, 2016 DOI: 10.3892/ol.2016.4913 Abstract. Gastric cancer is the fourth most frequent cancer and the second cause of cancer-related mortalities worldwide. Platelets play an important and multifaceted role in cancer progression. Elevated mean platelet volume (MPV) detected in peripheral blood has been identified in various types of cancer. In the present study, we investigated the application value of MPV in early diagnostic and prognostic prediction in patients with resectable gastric cancer. In total, 168 patients with resectable gastric cancer were included and separated into the gastric cancer and healthy control groups according to median preoperatic MPV value (MPV low, 

Mean platelet volume provides beneficial diagnostic and prognostic information for patients with resectable gastric cancer.

Gastric cancer is the fourth most frequent cancer and the second cause of cancer-related mortalities worldwide. Platelets play an important and multif...
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