International Journal of Gynecological Pathology 34:25–29, Lippincott Williams & Wilkins, Baltimore r 2014 International Society of Gynecological Pathologists
Case Report
Mature Cystic Teratoma of Ovary With Mucinous Epithelial Neoplasm and Malignant Mural Nodule. A Case Report and Review of the Literature Fiona Vernea,
M.B.B.S.
and Alex Volodarsky-Perel,
M.D.
Key Words: Ovary—Teratoma—Mural nodule—Mucinous neoplasm.
form of a mural nodule. This combination of components is extremely unusual.
Ovarian mature teratomas are of the most common of all ovarian neoplasms. These tumors of germ cell origin are composed of elements containing any or all of the 3 germ layers—ectoderm, mesoderm, and endoderm. Therefore, the architectural morphology and histology of these tumors can vary greatly. Malignant transformation of mature cystic teratomas (MCTs) has been well described in the literature. This is however, rare, occurring in up to 2% of cases (1,2). In cases where malignant transformation does occur, the patients are most commonly postmenopausal. Of cases with malignant transformation in a MCT, squamous cell carcinoma is most common, occurring in about 75% to 85% of cases with adenocarcinoma occurring in
Case Report
Mature Cystic Teratoma of Ovary With Mucinous Epithelial Neoplasm and Malignant Mural Nodule. A Case Report and Review of the Literature Fiona Vernea,
M.B.B.S.
and Alex Volodarsky-Perel,
M.D.
Key Words: Ovary—Teratoma—Mural nodule—Mucinous neoplasm.
form of a mural nodule. This combination of components is extremely unusual.
Ovarian mature teratomas are of the most common of all ovarian neoplasms. These tumors of germ cell origin are composed of elements containing any or all of the 3 germ layers—ectoderm, mesoderm, and endoderm. Therefore, the architectural morphology and histology of these tumors can vary greatly. Malignant transformation of mature cystic teratomas (MCTs) has been well described in the literature. This is however, rare, occurring in up to 2% of cases (1,2). In cases where malignant transformation does occur, the patients are most commonly postmenopausal. Of cases with malignant transformation in a MCT, squamous cell carcinoma is most common, occurring in about 75% to 85% of cases with adenocarcinoma occurring in
