Graefes Arch Clin Exp Ophthalmol DOI 10.1007/s00417-015-2962-x
PEDIATRICS
Magnetic resonance imaging in congenital Brown syndrome Jae Hyoung Kim & Jeong-Min Hwang
Received: 3 September 2014 / Revised: 26 January 2015 / Accepted: 2 February 2015 # Springer-Verlag Berlin Heidelberg 2015
Abstract Aims Our aim was to elucidate the etiology of Brown syndrome by evaluating the trochlea position, morphologic characteristics of the extraocular muscles including superior oblique muscle/tendon complex, and the presence of the cranial nerves (CN) III, IV, and VI using magnetic resonance imaging (MRI) in eight patients with unilateral congenital Brown syndrome and one patient with bilateral congenital Brown syndrome. Methods Nine consecutive patients diagnosed with congenital Brown syndrome had a comprehensive ocular examination and MRI for the CN III, CN VI, and the extraocular muscles. Five of the nine patients underwent additional high resolution MRI for CN IV. The distance from the annulus of Zinn to the trochlea was measured. Results Normal sized CN III, IV, and VI, as well as all extraocular muscles, could be identified bilaterally in all patients with available MRI. The distance from the annulus of Zinn to the trochlea was the same in both eyes. Conclusions The findings for our patients, particularly in those who underwent additional high resolution MRI, did not provide evidence of a lack of CN IV as a cause of Brown syndrome.
Keywords Congenital Brown syndrome . Magnetic resonance imaging . Superior oblique
J. H. Kim Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea J.
PEDIATRICS
Magnetic resonance imaging in congenital Brown syndrome Jae Hyoung Kim & Jeong-Min Hwang
Received: 3 September 2014 / Revised: 26 January 2015 / Accepted: 2 February 2015 # Springer-Verlag Berlin Heidelberg 2015
Abstract Aims Our aim was to elucidate the etiology of Brown syndrome by evaluating the trochlea position, morphologic characteristics of the extraocular muscles including superior oblique muscle/tendon complex, and the presence of the cranial nerves (CN) III, IV, and VI using magnetic resonance imaging (MRI) in eight patients with unilateral congenital Brown syndrome and one patient with bilateral congenital Brown syndrome. Methods Nine consecutive patients diagnosed with congenital Brown syndrome had a comprehensive ocular examination and MRI for the CN III, CN VI, and the extraocular muscles. Five of the nine patients underwent additional high resolution MRI for CN IV. The distance from the annulus of Zinn to the trochlea was measured. Results Normal sized CN III, IV, and VI, as well as all extraocular muscles, could be identified bilaterally in all patients with available MRI. The distance from the annulus of Zinn to the trochlea was the same in both eyes. Conclusions The findings for our patients, particularly in those who underwent additional high resolution MRI, did not provide evidence of a lack of CN IV as a cause of Brown syndrome.
Keywords Congenital Brown syndrome . Magnetic resonance imaging . Superior oblique
J. H. Kim Department of Radiology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea J.
