Lung Mechanics ahd Oxygen Consumption During Spontanedus Ventilation and severe Heart Failure* A-I. Christine Stock, M.D., F.C.C.R;t Donald W Davis, M.D., Ph.D.;+ John W Manning, Ph.D.;§ and Marquita L. R~nll

The effects of acute heart failure on lung mechanics and oxygen consumption (Vo.)during normocarbic spontaneous ventilation were studied in 21 anesthetized pigs. Heart failure severe enough to double oxygen extraction (O.ex) was induced with intravenous esmolol boluses and infusion. Compared to normal, the inspiratory elastic work of breathing (Wei)increased from 335±371 (X±SD) to 559±48 mm Hg-ml (p

Lung mechanics and oxygen consumption during spontaneous ventilation and severe heart failure.

The effects of acute heart failure on lung mechanics and oxygen consumption (VO2) during normocarbic spontaneous ventilation were studied in 21 anesth...
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