Australian and Newhttp://anp.sagepub.com/ Zealand Journal of Psychiatry
Low vitamin D levels are associated with symptoms of depression in young adult males Lucinda J Black, Peter Jacoby, Karina L Allen, Gina S Trapp, Prue H Hart, Susan M Byrne, Trevor A Mori, Lawrence J Beilin and Wendy H Oddy Aust N Z J Psychiatry published online 13 November 2013 DOI: 10.1177/0004867413512383 The online version of this article can be found at: http://anp.sagepub.com/content/early/2013/11/12/0004867413512383 A more recent version of this article was published on - May 1, 2014
Published by: http://www.sagepublications.com
On behalf of:
The Royal Australian and New Zealand College of Psychiatrists
Additional services and information for Australian and New Zealand Journal of Psychiatry can be found at: Email Alerts: http://anp.sagepub.com/cgi/alerts Subscriptions: http://anp.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav
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Downloaded from anp.sagepub.com at UNIV TORONTO on August 13, 2014
512383 2013
ANP00010.1177/0004867413512383ANZJP ArticlesBlack et al.
Research
Low vitamin D levels are associated with symptoms of depression in young adult males
Australian & New Zealand Journal of Psychiatry 00(0) 1–8 DOI: 10.1177/0004867413512383 © The Royal Australian and New Zealand College of Psychiatrists 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav anp.sagepub.com
Lucinda J Black1, Peter Jacoby1, Karina L Allen1,2, Gina S Trapp1, Prue H Hart1, Susan M Byrne2, Trevor A Mori3, Lawrence J Beilin3 and Wendy H Oddy1
Abstract Objective: Results from studies examining associations between serum 25-hydroxyvitamin D (25(OH)D) concentrations and depressive symptoms are equivocal. We investigated the relationship between serum 25(OH)D concentrations and symptoms of depression, anxiety and stress in a cross-sectional analysis of a population-based sample of young adults participating in the Western Australian Pregnancy Cohort (Raine) Study. Methods: Participants provided a blood sample at the 20-year follow-up (March 2010-April 2012) for the measurement of serum 25(OH)D concentrations. Mental health symptoms were assessed using the 21-item Depression Anxiety Stress Scales (DASS-21). Associations between serum 25(OH)D concentrations and total DASS-21 scores and subscale scores of depression, anxiety and stress were explored in males and females using negative binomial regression, adjusting for age, race, body mass index (BMI) and physical activity (n=735). Models examining subscale scores were also adjusted for the other subscale scores. Results: After adjusting for confounders, an increase in serum 25(OH)D concentrations of 10 nmol/L decreased total DASS-21 scores in males by 9% (rate ratio (RR) 0.91; 95%CI 0.87,0.95; p
Low vitamin D levels are associated with symptoms of depression in young adult males Lucinda J Black, Peter Jacoby, Karina L Allen, Gina S Trapp, Prue H Hart, Susan M Byrne, Trevor A Mori, Lawrence J Beilin and Wendy H Oddy Aust N Z J Psychiatry published online 13 November 2013 DOI: 10.1177/0004867413512383 The online version of this article can be found at: http://anp.sagepub.com/content/early/2013/11/12/0004867413512383 A more recent version of this article was published on - May 1, 2014
Published by: http://www.sagepublications.com
On behalf of:
The Royal Australian and New Zealand College of Psychiatrists
Additional services and information for Australian and New Zealand Journal of Psychiatry can be found at: Email Alerts: http://anp.sagepub.com/cgi/alerts Subscriptions: http://anp.sagepub.com/subscriptions Reprints: http://www.sagepub.com/journalsReprints.nav Permissions: http://www.sagepub.com/journalsPermissions.nav
Version of Record - May 1, 2014 >> OnlineFirst Version of Record - Nov 13, 2013 What is This?
Downloaded from anp.sagepub.com at UNIV TORONTO on August 13, 2014
512383 2013
ANP00010.1177/0004867413512383ANZJP ArticlesBlack et al.
Research
Low vitamin D levels are associated with symptoms of depression in young adult males
Australian & New Zealand Journal of Psychiatry 00(0) 1–8 DOI: 10.1177/0004867413512383 © The Royal Australian and New Zealand College of Psychiatrists 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav anp.sagepub.com
Lucinda J Black1, Peter Jacoby1, Karina L Allen1,2, Gina S Trapp1, Prue H Hart1, Susan M Byrne2, Trevor A Mori3, Lawrence J Beilin3 and Wendy H Oddy1
Abstract Objective: Results from studies examining associations between serum 25-hydroxyvitamin D (25(OH)D) concentrations and depressive symptoms are equivocal. We investigated the relationship between serum 25(OH)D concentrations and symptoms of depression, anxiety and stress in a cross-sectional analysis of a population-based sample of young adults participating in the Western Australian Pregnancy Cohort (Raine) Study. Methods: Participants provided a blood sample at the 20-year follow-up (March 2010-April 2012) for the measurement of serum 25(OH)D concentrations. Mental health symptoms were assessed using the 21-item Depression Anxiety Stress Scales (DASS-21). Associations between serum 25(OH)D concentrations and total DASS-21 scores and subscale scores of depression, anxiety and stress were explored in males and females using negative binomial regression, adjusting for age, race, body mass index (BMI) and physical activity (n=735). Models examining subscale scores were also adjusted for the other subscale scores. Results: After adjusting for confounders, an increase in serum 25(OH)D concentrations of 10 nmol/L decreased total DASS-21 scores in males by 9% (rate ratio (RR) 0.91; 95%CI 0.87,0.95; p
