Osteoporos Int (2015) 26:2423–2429 DOI 10.1007/s00198-015-3152-8

ORIGINAL ARTICLE

Low pulmonary function is related with a high risk of sarcopenia in community-dwelling older adults: the Korea National Health and Nutrition Examination Survey (KNHANES) 2008–2011 Y. K. Jeon 1,6 & M. J. Shin 2,6 & M. H. Kim 3,6 & J. H. Mok 3,6 & S. S. Kim 1,6 & B. H. Kim 1,6 & S.-J. Kim 4,6 & Y. K. Kim 5 & J. H. Chang 2,6 & Y. B. Shin 2,6 & I. J. Kim 1,6

Received: 17 November 2014 / Accepted: 26 April 2015 / Published online: 9 May 2015 # International Osteoporosis Foundation and National Osteoporosis Foundation 2015

Abstract Summary Sarcopenia is the age-related reduction of skeletal muscle mass in older individuals. Respiratory muscle strength may be related to skeletal muscle mass and, thus, the present study attempted to estimate the risk of sarcopenia relative to decreased pulmonary function. The present findings demonstrated that low pulmonary function was associated with low muscle mass in community-dwelling older adults. Introduction Lean body mass is related to pulmonary function in patients with chronic obstructive pulmonary disease (COPD). However, the relationship between muscle mass and pulmonary function in healthy older adults has yet to be clarified. Thus, the present study investigated the association of pulmonary function with muscle mass in an older community-dwelling Korean population. Methods This study included 463 disease-free subjects over 6 5 y e a r s o f a ge w h o un d e r w e n t a nt h r o p o m e t r i c

Y. K. Jeon and M. J. Shin contributed equally to this work. * I. J. Kim [email protected] 1

Division of Endocrinology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea

2

Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea

3

Division of Pulmonology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea

4

Department of Nuclear Medicine, Pusan National University School of Medicine, Busan, Korea

5

Kim Yong Ki Clinic, Busan, Korea

6

Medical Research Institute, Pusan National University, Busan, Korea

measurements, laboratory tests, spirometry, and the estimation of appendicular skeletal muscle (ASM) mass in the 2008– 2011 Korea National Health and Nutrition Examination Survey (KNHANES). Low muscle mass was defined as the value of ASM divided by height squared (ASM/height2) that was less than two standard deviations (SD) below the sex-specific mean of the young reference group. Results Forced expiratory volume in 1 s (FEV1[L]) and forced vital capacity (FVC[L]) were positively correlated with ASM/height2 in males (p