RESEARCH ARTICLE

Low 25(OH)-vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents Christiane Husmann1, Mirjam Frank2, Bo¨rge Schmidt2, Karl-Heinz Jo¨ckel2, Jochen Antel1, Volker Reissner1, Lars Libuda1, Johannes Hebebrand1, Manuel Fo¨cker1*

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1 Department of Child and Adolescent Psychiatry, University Hospital Essen, University Duisburg-Essen, Essen, Germany, 2 Institute for Medical Informatics, Biometry und Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany * [email protected]

Abstract OPEN ACCESS Citation: Husmann C, Frank M, Schmidt B, Jo¨ckel K-H, Antel J, Reissner V, et al. (2017) Low 25(OH)vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents. PLoS ONE 12(8): e0183091. https://doi.org/10.1371/journal. pone.0183091 Editor: Jacobus P. van Wouwe, TNO, NETHERLANDS

Background Evidence has accumulated for the association between low vitamin D serum concentrations and mental health disorders in both children and adults. We performed a cross-sectional analysis in a population-based sample of children and adolescents to detect associations between 25(OH)-vitamin D serum [25(OH)D] concentrations and scores of the five Strengths and Difficulties Questionnaire (SDQ) subscales and the total difficulties score in different age groups (age 3-

Low 25(OH)-vitamin D concentrations are associated with emotional and behavioral problems in German children and adolescents.

Evidence has accumulated for the association between low vitamin D serum concentrations and mental health disorders in both children and adults. We pe...
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