Table I-Predicted and Observed First-Pass Metabolism of Nortriptyline in Six Subjects

RESULTS

76 FP (Predicted)

AUC,pgl %FP liter X h r (Observed)

Subject ____

5 6 7 8 9 10 Mean

Blood Flow Model

Plasma Flow Model

38 39 37 45 38 27 37.33 f 2.38 4.02 p

Liquid chromatography in pharmaceutical analysis V: determination of an isoniazid-pyridoxine hydrochloride mixture.

Table I-Predicted and Observed First-Pass Metabolism of Nortriptyline in Six Subjects RESULTS 76 FP (Predicted) AUC,pgl %FP liter X h r (Observed)...
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