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Br. J. Cancer (1992), 57-61 66, 57-61 Br. J. Cancer (1992), 66,

Macmillan Press Ltd., 1992

Macmillan

Press

Ltd.,

1992

Lipid metabolism in cancer cachexia H.D. Mulligan, S.A. Beck & M.J. Tisdale CRC Experimental Chemotherapy Group, Pharmaceutical Sciences Institute, Aston University, Birmingham B4 7ET, UK. Summary The effect of cancer cachexia on the oxidative metabolism of lipids has been studied in mice transplanted either with the MAC16 adenocarcinoma, which induces profound loss of host body weight and depletion of lipid stores, or the MAC13 adenocarcinoma, which is of the same histological type, but which grows without an effect on host body weight or lipid stores. While oxidation of D-[U-'4C]glucose did not differ between animals bearing tumours of either type and non-tumour bearing controls, oxidation of [1-'4C]triolein administered by intragastric intubation was significantly (P

Lipid metabolism in cancer cachexia.

The effect of cancer cachexia on the oxidative metabolism of lipids has been studied in mice transplanted either with the MAC16 adenocarcinoma, which ...
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