Br. J. Cancer (1992), 57-61 66, 57-61 Br. J. Cancer (1992), 66,
Macmillan Press Ltd., 1992
Macmillan
Press
Ltd.,
1992
Lipid metabolism in cancer cachexia H.D. Mulligan, S.A. Beck & M.J. Tisdale CRC Experimental Chemotherapy Group, Pharmaceutical Sciences Institute, Aston University, Birmingham B4 7ET, UK. Summary The effect of cancer cachexia on the oxidative metabolism of lipids has been studied in mice transplanted either with the MAC16 adenocarcinoma, which induces profound loss of host body weight and depletion of lipid stores, or the MAC13 adenocarcinoma, which is of the same histological type, but which grows without an effect on host body weight or lipid stores. While oxidation of D-[U-'4C]glucose did not differ between animals bearing tumours of either type and non-tumour bearing controls, oxidation of [1-'4C]triolein administered by intragastric intubation was significantly (P
The effect of cancer cachexia on the oxidative metabolism of lipids has been studied in mice transplanted either with the MAC16 adenocarcinoma, which ...