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Oncology 1991;48:128-130
Leukocyte Alkaline Phosphatase and Carcinoembryonic Antigen in Colorectal Cancer Patients (Usefulness in the Assessment of the Stage) Nat alio Walacha , Amiram Guterman*, Jacob L. Zaidman b , Suzana Kaufman c , Sally ScharJ* Departments of “ Oncology. b Biochemical Pathology, and c Hematology. Assaf Harofeh Medical Center. Zcrifin; d Department of Oncology, Sheba Medical Center. Tel Hashomer. Sackler School of Medicine. Tel Aviv University, Israel
Key Words. Leukocyte alkaline phosphatase • Carcinoembryonic antigen • Colorectal cancer Abstract. Leukocyte alkaline phosphatase (LAP) scores in peripheral blood, and plasma carcinoembryonic antigen (CEA) levels were determined in 122 colorectal cancer patients, and compared to 30 healthy persons, who served as controls. Both markers are gradually elevated according to the severity of tumor penetration. LAP scores in Dukes'C and D (157 + 79) were significantly higher than in Dukes'A, Bi and B2 (81 + 43), p < 0.001. CEA levels were also higher in Dukes' C and D (50 ± 95) than in patients with Dukes' A, Bi and B2 (25 ± 54), p
Oncology 1991;48:128-130
Leukocyte Alkaline Phosphatase and Carcinoembryonic Antigen in Colorectal Cancer Patients (Usefulness in the Assessment of the Stage) Nat alio Walacha , Amiram Guterman*, Jacob L. Zaidman b , Suzana Kaufman c , Sally ScharJ* Departments of “ Oncology. b Biochemical Pathology, and c Hematology. Assaf Harofeh Medical Center. Zcrifin; d Department of Oncology, Sheba Medical Center. Tel Hashomer. Sackler School of Medicine. Tel Aviv University, Israel
Key Words. Leukocyte alkaline phosphatase • Carcinoembryonic antigen • Colorectal cancer Abstract. Leukocyte alkaline phosphatase (LAP) scores in peripheral blood, and plasma carcinoembryonic antigen (CEA) levels were determined in 122 colorectal cancer patients, and compared to 30 healthy persons, who served as controls. Both markers are gradually elevated according to the severity of tumor penetration. LAP scores in Dukes'C and D (157 + 79) were significantly higher than in Dukes'A, Bi and B2 (81 + 43), p < 0.001. CEA levels were also higher in Dukes' C and D (50 ± 95) than in patients with Dukes' A, Bi and B2 (25 ± 54), p
