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To estimate the incidence values at time t = 0, we can assume a proportional relation with time. The estimated value of the incidence at time t = 0 for men is 0.0137 x (1 - 0.14) = 0.0118 and 0.0062 (1 - 0.37) = 0.0039 for women, . Table 1 summarizes the data. Table 2 summarizes the values of relative risk in men (numerator) and women (denominator) at different times of the studies. It can be seen that the values computed from the two types of studies are very close and that the relative risk decreases as the population ages. We can conclude that when data from prevalence and incidence studies are to be

compared, the prevalence study should be done in the middle of the prospective study. In this way, age-related changes in the rates would not influence the comparison. REFERENCE

1. Beaglehole R, Heiss G, Tyroler HA, et al: Prevalence and incidence data in the assessment of the risk of coronary heart disease. Am J Epidemiol 102:55-62, 1975

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EPIDEMIOLOGIC STUDIES OF CORONARY HEART DISEASE AND STROKE IN JAPANESE MEN LIVING IN JAPAN, HAWAII, AND CALIFORNIA: ADDITIONAL ACKNOWLEDGMENTS In his thoughtful commentary which introduced the report of our collaborative study of men of Japanese ancestry living in Japan, Hawaii and California (Am J Epidemiol, 102:469-476, 1975), Professor Donald Reid referred to the logistic and conceptual problems involved in mounting an international collaborative study. In any large, complex, long-term study, the authors of the published reports are most commonly those who analyze and write up the data. These are not necessarily the same people who conceived and began the study. Both groups of investigators are important, and it would be unpardonable to recognize the contribution of the former while neglecting the latter. In the series of papers published, we neglected to give adequate tribute to many individuals who played crucial roles in the conception, design and execution of this collaborative study. In particular we should like to acknowledge the creative leadership of Dr. Reuel A. Stallones, Dean of the School of Public Health of the University of Texas. In 1963

and 1964, during visits to Hiroshima, Dr. Stallones developed the protocols that subsequently formed the basis for the threepart study. From that date until his departure from Berkeley in 1968, he was intimately involved in every phase of the collaborative study and was responsible for the design and initiation of the California component. Dr. William J. Zukel, Director of the Clinical Applications Division of the National Heart and Lung Institute, has been responsible from the very beginning for continued support of the research that was reported in the published series of papers. Mr. Tavia Gordon, Supervisory Statistician of the National Heart and Lung Institute has made valuable contributions to the conduct of these studies from their inception. More recently, Dr. Manning Feinleib, Chief of the Epidemiology Branch of the NHLI, has played an important role in supporting the ongoing research. We should like to gratefully acknowledge their support. We should also like to publicly recognize

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the contribution of many other individuals: from the National Heart and Lung Institute, Harold Kahn, Jeanne Tillotson and Jacob Lieberman; from the Atomic Bomb Casualty Commission, Drs. George B. Darling, Katsuhiko Yano, Benedict R. Harris, Kenneth G. Johnson, Gilbert A. Beebe, Donald S. Dock, Thomas L. Robertson, and Seymour Jablon; from the Honolulu Heart Study, Drs. Robert C. Moellering, James D. Trombold, Laurence J. McCarthy, Roland L. Phillips, David C Miller, and Gary A. Glober; from the University of California, Berkeley, Dr.

Judith B. Cohen, Miss Beatrice R. Treiman, Mr. John Hoben, Drs. Michael L. Gay and Loring G. Dales. Without these many individuals and others, these studies could not have been carried out. S. Leonard Syme Michael G. Marmot Abraham Kagan Hiroo Kato George Rhoads School of Public Health U. of California Berkeley, CA 94720

Letter: Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii, and California: additional acknowledgments.

223 LETTERS TO THE EDITOR To estimate the incidence values at time t = 0, we can assume a proportional relation with time. The estimated value of th...
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