Alimentary Pharmacology and Therapeutics

Letter to the Editor Letter: coeliac disease in inter-tropical Africa T. Coton

It is our duty to warn practitioners who manage sub-Saharan immigrants that coeliac disease can be found in these patients.

Digestive Pathology Unit, H^ opital d’Instruction des Armees Laveran, 13384 Marseille Cedex 13, France. E-mail: [email protected]

ACKNOWLEDGEMENT Declaration of personal and funding interests: None.

doi:10.1111/apt.12525

REFERENCES

SIRS, I read with interest the paper by Kang et al. about the prevalence of coeliac disease.1 They did not discuss the recent publications about coeliac disease in sub-Saharan East Africa, especially in Sudan and Djibouti.2, 3, 4 Coeliac disease does exist in inter-tropical Africa, even if HLA DQ2 and DQ8 haplotypes do seem less frequent and coeliac disease seroprevalence is lower in general population.1, 5 We recently published 17 cases of patients with coeliac disease seen in Djibouti between 2005 and 2007. Unfortunately, we could not determine HLA DQ2 and DQ8 status in this population due to lack of finance.6

1. Kang JY, Kang AHY, Green A, Gwee KA, Ho KY. Systematic review: worldwide variation in the frequency of celiac disease and changes over time. Aliment Pharmacol Ther 2013; 38: 226–45. 2. Suliman GI. Celiac disease in Sudanese children. Gut 1978; 19: 121–5. 3. Ageep AK. Celiac disease in the Red Sea state of Sudan. Trop Gastroenterol 2012; 33: 118–22. 4. Mohammed IM, Karrar ZE, El Safi SH. Celiac disease in Sudanese children with clinical feature suggestive of the disease. East Mediterr Health J 2006; 12: 582–9. 5. Cataldo F, Lio D, Simpore J, et al. Consumption of wheat foodstuffs not a risk for celiac disease occurrence in Burkina Faso. J Pediatr Gastroenterol Nutr 2002; 35: 233–4. 6. Diallo I, Coton T. Celiac disease: a challenging disease uneasy to diagnose in Sub-Saharan Africa. J Gastroenterol Hepatol Res 2013; 2: 753–6.

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Letter: coeliac disease in inter-tropical Africa.

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