American Journal of Pharmaceutical Education 2014; 78 (2) Article 37.
INSTRUCTIONAL DESIGN AND ASSESSMENT Laboratory Exercises to Teach Clinically Relevant Chemistry of Antibiotics Khalid A. El Sayed, PhD, and Candace T. Chelette, PharmD School of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana Submitted January 14, 2013; accepted August 26, 2013; published March 12, 2014.
Objectives. To design, implement, and evaluate student performance on clinically relevant chemical and spectral laboratory exercises on antibiotics. Design. In the first of 2 exercises, second-year pharmacy students enrolled in an integrated laboratory sequence course studied the aqueous stability of ß-lactam antibiotics using a spectral visual approach. In a second exercise, students studied the tendency of tetracycline, rifamycins, and fluoroquinolones to form insoluble chelate complexes (turbidity) with polyvalent metals. Assessment. On a survey to assess achievement of class learning objectives, students agreed the laboratory activities helped them better retain important information concerning antibiotic stability and interactions. A significant improvement was observed in performance on examination questions related to the laboratory topics for 2012 and 2013 students compared to 2011 students who did not complete the laboratory. A 1-year follow-up examination question administered in a separate course showed >75% of the students were able to identify rifamycins-food interactions compared with
INSTRUCTIONAL DESIGN AND ASSESSMENT Laboratory Exercises to Teach Clinically Relevant Chemistry of Antibiotics Khalid A. El Sayed, PhD, and Candace T. Chelette, PharmD School of Pharmacy, University of Louisiana at Monroe, Monroe, Louisiana Submitted January 14, 2013; accepted August 26, 2013; published March 12, 2014.
Objectives. To design, implement, and evaluate student performance on clinically relevant chemical and spectral laboratory exercises on antibiotics. Design. In the first of 2 exercises, second-year pharmacy students enrolled in an integrated laboratory sequence course studied the aqueous stability of ß-lactam antibiotics using a spectral visual approach. In a second exercise, students studied the tendency of tetracycline, rifamycins, and fluoroquinolones to form insoluble chelate complexes (turbidity) with polyvalent metals. Assessment. On a survey to assess achievement of class learning objectives, students agreed the laboratory activities helped them better retain important information concerning antibiotic stability and interactions. A significant improvement was observed in performance on examination questions related to the laboratory topics for 2012 and 2013 students compared to 2011 students who did not complete the laboratory. A 1-year follow-up examination question administered in a separate course showed >75% of the students were able to identify rifamycins-food interactions compared with
