JID VisualDX Quiz

JID VisualDx Quiz: January 2014 Sonal Choudhary1 and Robert S. Kirsner1 Journal of Investigative Dermatology (2014) 134, e12; doi:10.1038/jid.2013.458

JID and Logical Images, Inc., have cooperated to offer the JID VisualDx Quiz, incorporating diagnostic images from VisualDx’s vast database. Questions relate to the image as well as to selected articles in JID, which are listed after the questions. Answers will be posted as supplementary material. We hope you enjoy this challenge.

Image appears with permission from VisualDx. © Logical Images, Inc.

QUESTIONS 1.  What is your diagnosis?  a.  Epidermolytic hyperkeratosis.  b.  Atopic dermatitis.  c.  Staphylococcus scalded skin syndrome.  d.  Cutaneous T-cell lymphoma.  e.  Tinea corporis.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA

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© 2014 The Society for Investigative Dermatology

www.jidonline.org

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JID VisualDx Quiz

2.  Which of the following is true of filaggrin (FLG) mutations and atopic dermatitis (AD)?  a. FLG mutations are seen in all patients.  b. FLG mutations are the only cause of barrier dysfunction in patients with AD.   c.  Climate has an effect on AD in patients with FLG mutations.   d.  The majority of patients with AD have FLG mutations.  e.  Persons with FLG mutations are at increased risk of developing AD.

3. Data from the study by Sargen et al. suggest that which of the following regarding climate and AD is true?  a.  Temperature, humidity, and sun exposure are all independent predictors of AD severity.  b.  Patients with AD have worse disease in rainy climates.  c.  Patients with AD have worse disease in places with high amounts of sun exposure.  d.  Temperature, humidity, and sun exposure exacerbate AD.  e.  Temperature, humidity, and sun exposure increase the risk of cancer in patients using calcineurin inhibitors.

TOPIC ARTICLE Questions 2 and 3 refer to the following article: Sargen MR, Hoffstad O, Margolis DJ (2013) Warm, humid, and high sun exposure climates are associated with poorly controlled eczema: PEER (Pediatric Eczema Elective Registry) Cohort, 2004–2012. J Invest Dermatol 134:51–57

Answers are available as supplementary material at http://dx.doi.org/10.1038/jid.2013.458. Additional images related to this condition and the differential diagnosis may be found at http://info.visualdx.com/l/11412/2013-10-07/tln4w

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Journal of Investigative Dermatology (2014), Volume 134

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JID VisualDx Quiz: January 2014.

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